257292

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 390294..390892 Replicon plasmid pM103b
Accession NZ_CP104128
Organism Sinorhizobium sp. M103

Toxin (Protein)


Gene name relE Uniprot ID Q930F0
Locus tag N0Q90_RS21555 Protein ID WP_010967243.1
Coordinates 390294..390587 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N0Q90_RS21560 Protein ID WP_275598527.1
Coordinates 390584..390892 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0Q90_RS21525 (N0Q90_21530) 385799..386041 + 243 WP_275598523.1 hypothetical protein -
N0Q90_RS21530 (N0Q90_21535) 386090..386185 + 96 Protein_384 cold-shock protein -
N0Q90_RS21535 (N0Q90_21540) 386443..386835 - 393 WP_275598524.1 response regulator -
N0Q90_RS21540 (N0Q90_21545) 387043..388173 - 1131 WP_275598525.1 IS1595 family transposase -
N0Q90_RS21545 (N0Q90_21550) 388341..388642 - 302 Protein_387 plasmid partitioning protein RepB C-terminal domain-containing protein -
N0Q90_RS21550 (N0Q90_21555) 388833..390033 + 1201 Protein_388 NAD-dependent formate dehydrogenase -
N0Q90_RS21555 (N0Q90_21560) 390294..390587 - 294 WP_010967243.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
N0Q90_RS21560 (N0Q90_21565) 390584..390892 - 309 WP_275598527.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N0Q90_RS21565 (N0Q90_21570) 391098..391526 - 429 WP_275598528.1 GNAT family N-acetyltransferase -
N0Q90_RS21570 (N0Q90_21575) 392538..392654 - 117 Protein_392 cation transporter -
N0Q90_RS21575 (N0Q90_21580) 392853..393386 + 534 Protein_393 short-chain dehydrogenase -
N0Q90_RS21580 (N0Q90_21585) 393571..393798 - 228 WP_003525968.1 hypothetical protein -
N0Q90_RS21585 (N0Q90_21590) 393875..394768 - 894 WP_275598529.1 AraC family transcriptional regulator -
N0Q90_RS21590 (N0Q90_21595) 394981..395382 - 402 WP_275598530.1 periplasmic heavy metal sensor -
N0Q90_RS21595 (N0Q90_21600) 395379..395828 - 450 WP_275598531.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..772647 772647
- flank IS/Tn - - 387043..388173 1130


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-60)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11278.93 Da        Isoelectric Point: 6.4734

>T257292 WP_010967243.1 NZ_CP104128:c390587-390294 [Sinorhizobium sp. M103]
MRLVWARYALDDRDTIFSYIERENPRAAVHVDEEIVSAVRRLLDFPESGRPGRIAGTRELVIPRTPYIAAYMVMEDRIRI
LRVLHGAQKWPSELDDG

Download         Length: 294 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11224.61 Da        Isoelectric Point: 5.6604

>AT257292 WP_275598527.1 NZ_CP104128:c390892-390584 [Sinorhizobium sp. M103]
MASNALVQTRIDAEIKERATAVLENMGLTVSDAVRILLTRTANEGALPLELFSHSEAHDAWFRAKVLRALEDTRPDVDDA
DADAHFRERRAAALRKAAAGDR

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q930F0

Antitoxin

Source ID Structure

References