257286

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 432303..432856 Replicon chromosome
Accession NZ_CP104126
Organism Sinorhizobium sp. M103

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N0Q90_RS02110 Protein ID WP_244563892.1
Coordinates 432303..432557 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N0Q90_RS02115 Protein ID WP_085026101.1
Coordinates 432584..432856 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0Q90_RS02065 (N0Q90_02065) 427361..427798 + 438 Protein_412 thermonuclease family protein -
N0Q90_RS02070 (N0Q90_02070) 428004..428261 + 258 WP_275596385.1 WGR domain-containing protein -
N0Q90_RS02075 (N0Q90_02075) 428359..428493 - 135 WP_275596284.1 hypothetical protein -
N0Q90_RS02080 (N0Q90_02080) 428836..428961 + 126 WP_275531997.1 hypothetical protein -
N0Q90_RS02085 (N0Q90_02085) 429257..429568 - 312 WP_085026105.1 DUF736 domain-containing protein -
N0Q90_RS02090 (N0Q90_02090) 429956..430189 + 234 WP_275599812.1 hypothetical protein -
N0Q90_RS02095 (N0Q90_02095) 430222..430314 - 93 Protein_418 antirestriction protein ArdC -
N0Q90_RS02100 (N0Q90_02100) 430409..431020 - 612 WP_275596283.1 tyrosine-type recombinase/integrase -
N0Q90_RS02105 (N0Q90_02105) 431349..431693 - 345 Protein_420 hypothetical protein -
N0Q90_RS02110 (N0Q90_02110) 432303..432557 - 255 WP_244563892.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N0Q90_RS02115 (N0Q90_02115) 432584..432856 - 273 WP_085026101.1 CopG family ribbon-helix-helix protein Antitoxin
N0Q90_RS02120 (N0Q90_02120) 433023..433327 - 305 Protein_423 hypothetical protein -
N0Q90_RS02125 (N0Q90_02125) 433847..434725 - 879 WP_275596282.1 SDR family oxidoreductase -
N0Q90_RS02130 (N0Q90_02130) 434877..435246 + 370 Protein_425 helix-turn-helix domain-containing protein -
N0Q90_RS02135 (N0Q90_02135) 435640..436665 - 1026 WP_275596281.1 zincin-like metallopeptidase domain-containing protein -
N0Q90_RS02140 (N0Q90_02140) 436920..437723 - 804 WP_275596280.1 sulfite exporter TauE/SafE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 369359..437723 68364


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-82)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9503.79 Da        Isoelectric Point: 6.7167

>T257286 WP_244563892.1 NZ_CP104126:c432557-432303 [Sinorhizobium sp. M103]
MERCRRFLATKAPEAARRAGQAIERQFLLLETAPDIGRPFSEAPELRELVIAFGDSGYVALYHHQPADDAVYVLAFRHQK
EAGY

Download         Length: 255 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10571.87 Da        Isoelectric Point: 6.7205

>AT257286 WP_085026101.1 NZ_CP104126:c432856-432584 [Sinorhizobium sp. M103]
MATSLKIDDTLKSRVQQLASQRRRSPHWIMLEAIQQYVEREEARESFKQEALASWAAYKETGRHLTGEEVRTWLTTWGTD
DEKPVPECHK

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References