Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1929306..1929451 Replicon chromosome
Accession NZ_CP104110
Organism Klebsiella pneumoniae strain USDA-ARS-USMARC-52099

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1929342..1929444 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1929306..1929451 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N1708_RS09220 1924436..1926496 + 2061 WP_218790307.1 oligopeptidase B -
N1708_RS09225 1926500..1927159 - 660 WP_002911407.1 exodeoxyribonuclease X -
N1708_RS09230 1927238..1927468 - 231 WP_002911406.1 DNA polymerase III subunit theta -
N1708_RS09235 1927581..1927955 + 375 WP_004151448.1 CopC domain-containing protein YobA -
N1708_RS09240 1927959..1928828 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
N1708_RS09245 1928845..1929183 + 339 WP_075647430.1 YebY family protein -
- 1929306..1929451 - 146 - - Antitoxin
- 1929342..1929444 + 103 - - Toxin
N1708_RS09250 1929820..1929963 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
N1708_RS09255 1930068..1931036 - 969 WP_014907334.1 VirK/YbjX family protein -
N1708_RS09260 1931193..1931846 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
N1708_RS09265 1931843..1932034 - 192 WP_002911395.1 YebW family protein -
N1708_RS09270 1932132..1932371 - 240 WP_002911393.1 YebV family protein -
N1708_RS09275 1932487..1933920 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T257182 NZ_CP104110:1929342-1929444 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT257182 NZ_CP104110:c1929451-1929306 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References