Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 762686..763349 Replicon chromosome
Accession NZ_CP104108
Organism Cronobacter sakazakii strain USDA-ARS-USMARC-54664

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag N1710_RS03675 Protein ID WP_032987888.1
Coordinates 762933..763349 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A3Q9CFW7
Locus tag N1710_RS03670 Protein ID WP_007870701.1
Coordinates 762686..762952 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N1710_RS03645 (N1710_03645) 757715..759148 - 1434 WP_032987892.1 6-phospho-beta-glucosidase -
N1710_RS03650 (N1710_03650) 759300..760028 - 729 WP_004385670.1 MurR/RpiR family transcriptional regulator -
N1710_RS03655 (N1710_03655) 760205..760519 + 315 WP_080321077.1 N(4)-acetylcytidine aminohydrolase -
N1710_RS03660 (N1710_03660) 760661..761314 + 654 WP_007777939.1 hemolysin III family protein -
N1710_RS03665 (N1710_03665) 761419..762408 - 990 WP_105546331.1 tRNA-modifying protein YgfZ -
N1710_RS03670 (N1710_03670) 762686..762952 + 267 WP_007870701.1 FAD assembly factor SdhE Antitoxin
N1710_RS03675 (N1710_03675) 762933..763349 + 417 WP_032987888.1 protein YgfX Toxin
N1710_RS03680 (N1710_03680) 763363..763884 - 522 WP_105546330.1 flavodoxin FldB -
N1710_RS03685 (N1710_03685) 763986..764882 + 897 WP_087600150.1 site-specific tyrosine recombinase XerD -
N1710_RS03690 (N1710_03690) 764905..765624 + 720 WP_004385678.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
N1710_RS03695 (N1710_03695) 765628..767361 + 1734 WP_007870697.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16441.44 Da        Isoelectric Point: 11.4887

>T257169 WP_032987888.1 NZ_CP104108:762933-763349 [Cronobacter sakazakii]
VVLWHSDLRVSWRSQWLSLLLHGAVAVIILLLPWPLRYLPVWMLLLSLVVFDCVRSQRRINAFQGEVSLTADYHLRWQGV
DWQICATPWMLRSGMMLRLRHPKTTRRHHVWLAADSMTEAEWRDLRRLLLQQPVGDKR

Download         Length: 417 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10411.89 Da        Isoelectric Point: 4.8310

>AT257169 WP_007870701.1 NZ_CP104108:762686-762952 [Cronobacter sakazakii]
MDINNKARIHWACRRGMRELDISIMPFFEYDYDSLSDEDKRVFVRLLECDDPDLFNWLMNHGKPADAELARMVELIQQRN
QARGPVAL

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9CFW7

References