Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 599860..600379 Replicon chromosome
Accession NZ_CP104108
Organism Cronobacter sakazakii strain USDA-ARS-USMARC-54664

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N1710_RS02885 Protein ID WP_105546376.1
Coordinates 600092..600379 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N1710_RS02880 Protein ID WP_004385270.1
Coordinates 599860..600102 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N1710_RS02865 (N1710_02865) 595903..597021 + 1119 WP_004385267.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
N1710_RS02870 (N1710_02870) 597018..597758 + 741 WP_004385268.1 KDGP aldolase family protein -
N1710_RS02875 (N1710_02875) 597872..599782 + 1911 WP_004385269.1 PRD domain-containing protein -
N1710_RS02880 (N1710_02880) 599860..600102 + 243 WP_004385270.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N1710_RS02885 (N1710_02885) 600092..600379 + 288 WP_105546376.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N1710_RS02890 (N1710_02890) 600387..600851 - 465 WP_007871043.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
N1710_RS02895 (N1710_02895) 601147..603282 - 2136 WP_104676904.1 anaerobic ribonucleoside-triphosphate reductase -
N1710_RS02900 (N1710_02900) 603579..604460 - 882 WP_007871040.1 LysR family transcriptional regulator -
N1710_RS02905 (N1710_02905) 604563..605093 + 531 WP_105546375.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10839.85 Da        Isoelectric Point: 10.5836

>T257168 WP_105546376.1 NZ_CP104108:600092-600379 [Cronobacter sakazakii]
MSYKLVFDPRALKEWHKLGETVKAQFKKKLAHVLAAPRVKSARLSGLPDCYKIKLRTSGYRLVYQVRDDAVCVLVIAIGK
RENLTVYQGVGHRLE

Download         Length: 288 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9037.45 Da        Isoelectric Point: 5.1088

>AT257168 WP_004385270.1 NZ_CP104108:599860-600102 [Cronobacter sakazakii]
MATINVRLDDKLKNEAYAVLEKLGITPTEAVRLLFQYVAQNGRMPVKTLTVSDSEEALLRTVRERLADPRPGIRVDLDEL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References