Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 217044..217510 Replicon chromosome
Accession NZ_CP104108
Organism Cronobacter sakazakii strain USDA-ARS-USMARC-54664

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N1710_RS00990 Protein ID WP_054625504.1
Coordinates 217044..217319 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N1710_RS00995 Protein ID WP_054625503.1
Coordinates 217319..217510 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N1710_RS00975 (N1710_00975) 213144..213986 - 843 WP_004388308.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
N1710_RS00980 (N1710_00980) 214179..216221 + 2043 WP_014727863.1 oligopeptidase A -
N1710_RS00985 (N1710_00985) 216230..216982 + 753 WP_038858682.1 16S rRNA (guanine(1516)-N(2))-methyltransferase RsmJ -
N1710_RS00990 (N1710_00990) 217044..217319 - 276 WP_054625504.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N1710_RS00995 (N1710_00995) 217319..217510 - 192 WP_054625503.1 hypothetical protein Antitoxin
N1710_RS01000 (N1710_01000) 217685..218122 - 438 WP_004388310.1 universal stress protein UspA -
N1710_RS01005 (N1710_01005) 218517..218852 + 336 WP_004388311.1 universal stress protein UspB -
N1710_RS01010 (N1710_01010) 218903..220405 - 1503 WP_004388312.1 inorganic phosphate transporter PitA -
N1710_RS01015 (N1710_01015) 220635..221825 + 1191 WP_105568401.1 NAD(P)/FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10481.18 Da        Isoelectric Point: 5.6662

>T257167 WP_054625504.1 NZ_CP104108:c217319-217044 [Cronobacter sakazakii]
MLPIRWTEEAKMDLFALISFIASDNPGAAQALLTRIEESILPAAYYPEMFREGRVPDTREIIAHPNYIVVYKVTSEYLLV
LSVLHARQRYP

Download         Length: 276 bp

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7188.24 Da        Isoelectric Point: 10.7020

>AT257167 WP_054625503.1 NZ_CP104108:c217510-217319 [Cronobacter sakazakii]
MPKHDSPGVSSRKTHKQAEQYELWFREKVEAAAASRQPITPHDDVMASARKIIESAKVRRKMA

Download         Length: 192 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References