Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4823211..4823896 Replicon chromosome
Accession NZ_CP104107
Organism Pseudomonas mosselii strain PH4

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag N0U38_RS21940 Protein ID WP_260270432.1
Coordinates 4823211..4823579 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag N0U38_RS21945 Protein ID WP_260270433.1
Coordinates 4823576..4823896 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0U38_RS21910 (N0U38_21910) 4818700..4819425 + 726 WP_011532417.1 LPS export ABC transporter ATP-binding protein -
N0U38_RS21915 (N0U38_21915) 4819599..4821098 + 1500 WP_028689657.1 RNA polymerase factor sigma-54 -
N0U38_RS21920 (N0U38_21920) 4821177..4821485 + 309 WP_011532415.1 ribosome-associated translation inhibitor RaiA -
N0U38_RS21925 (N0U38_21925) 4821498..4821974 + 477 WP_260270430.1 PTS IIA-like nitrogen regulatory protein PtsN -
N0U38_RS21930 (N0U38_21930) 4821965..4822819 + 855 WP_062572910.1 RNase adapter RapZ -
N0U38_RS21935 (N0U38_21935) 4822840..4823112 + 273 WP_260270431.1 HPr family phosphocarrier protein -
N0U38_RS21940 (N0U38_21940) 4823211..4823579 + 369 WP_260270432.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N0U38_RS21945 (N0U38_21945) 4823576..4823896 + 321 WP_260270433.1 helix-turn-helix transcriptional regulator Antitoxin
N0U38_RS21950 (N0U38_21950) 4823936..4824829 - 894 WP_260272033.1 ZIP family metal transporter -
N0U38_RS21955 (N0U38_21955) 4824841..4825452 - 612 WP_062572908.1 superoxide dismutase -
N0U38_RS21960 (N0U38_21960) 4825454..4825915 - 462 WP_062572907.1 hypothetical protein -
N0U38_RS21965 (N0U38_21965) 4825941..4827317 - 1377 WP_260270434.1 class II fumarate hydratase -
N0U38_RS21970 (N0U38_21970) 4827310..4827711 - 402 WP_186735137.1 FagA protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(18-111)

Antitoxin

HigA2-like, helix-turn-helix domain

(11-90)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13500.56 Da        Isoelectric Point: 9.7622

>T257166 WP_260270432.1 NZ_CP104107:4823211-4823579 [Pseudomonas mosselii]
MESDRQPKPLYWVASSKKDLLCLPEDIQQTVGFALHLAQTGSRHLQAKVLKGFSGAGVLEVVEDHDGNTYRAVYTVRLGA
AVYVLHCFQKKSKAGIRTPETDIALVRKRLKLAQAHSEGIQT

Download         Length: 369 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11698.69 Da        Isoelectric Point: 10.0577

>AT257166 WP_260270433.1 NZ_CP104107:4823576-4823896 [Pseudomonas mosselii]
MSEIEQGSGNVYADLNYPDADEMLVKARLASKICSIIKARHLTQMQAAQILGLPQPKVSEMTRGKFRGISESKMIDCLAR
LGRDVQIVVKAAPRSRPQGRVEVIFA

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References