Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2624319..2624590 Replicon chromosome
Accession NZ_CP104077
Organism Escherichia coli strain HB42

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2624357..2624459 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2624319..2624590 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0M81_RS12435 2621476..2622915 + 1440 WP_024179479.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
N0M81_RS12440 2623033..2623269 + 237 WP_001295499.1 YebV family protein -
N0M81_RS12445 2623374..2623565 + 192 WP_001296140.1 YebW family protein -
N0M81_RS12450 2623566..2624222 - 657 WP_000812752.1 protein-serine/threonine phosphatase -
- 2624319..2624590 + 272 - - Antitoxin
- 2624357..2624459 - 103 - - Toxin
N0M81_RS12455 2624618..2624959 - 342 WP_000976484.1 YebY family protein -
N0M81_RS12460 2624972..2625844 - 873 WP_000879323.1 copper homeostasis membrane protein CopD -
N0M81_RS12465 2625848..2626222 - 375 WP_000168737.1 CopC domain-containing protein YobA -
N0M81_RS12470 2626361..2626591 + 231 WP_000916763.1 DNA polymerase III subunit theta -
N0M81_RS12475 2626693..2627349 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
N0M81_RS12480 2627373..2628035 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T257122 NZ_CP104077:c2624459-2624357 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT257122 NZ_CP104077:2624319-2624590 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References