257103

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3494480..3495140 Replicon chromosome
Accession NZ_CP104049
Organism Salmonella enterica subsp. enterica serovar Kentucky strain Sal-FJ2064

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag NXZ70_RS16935 Protein ID WP_000244756.1
Coordinates 3494480..3494893 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag NXZ70_RS16940 Protein ID WP_000351186.1
Coordinates 3494874..3495140 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXZ70_RS16915 (3490421) 3490421..3492154 - 1734 WP_023223830.1 single-stranded-DNA-specific exonuclease RecJ -
NXZ70_RS16920 (3492160) 3492160..3492873 - 714 WP_023223829.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NXZ70_RS16925 (3492897) 3492897..3493793 - 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
NXZ70_RS16930 (3493906) 3493906..3494427 + 522 WP_001055885.1 flavodoxin FldB -
NXZ70_RS16935 (3494480) 3494480..3494893 - 414 WP_000244756.1 protein YgfX Toxin
NXZ70_RS16940 (3494874) 3494874..3495140 - 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
NXZ70_RS16945 (3495390) 3495390..3496370 + 981 WP_000874178.1 tRNA-modifying protein YgfZ -
NXZ70_RS16950 (3496486) 3496486..3497145 - 660 WP_000250289.1 hemolysin III family protein -
NXZ70_RS16955 (3497309) 3497309..3497620 - 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
NXZ70_RS16960 (3497778) 3497778..3499211 + 1434 WP_001230143.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T257103 WP_000244756.1 NZ_CP104049:c3494893-3494480 [Salmonella enterica subsp. enterica serovar Kentucky]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT257103 WP_000351186.1 NZ_CP104049:c3495140-3494874 [Salmonella enterica subsp. enterica serovar Kentucky]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References