257091

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 5971547..5973255 Replicon chromosome
Accession NZ_CP104045
Organism Pseudomonas sp. FJ2-5-13

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag N2A98_RS26670 Protein ID WP_275622825.1
Coordinates 5971547..5972425 (+) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag N2A98_RS26675 Protein ID WP_003195671.1
Coordinates 5972422..5973255 (+) Length 278 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2A98_RS26645 (N2A98_26670) 5967553..5968389 + 837 WP_050499539.1 ABC transporter ATP-binding protein -
N2A98_RS26650 (N2A98_26675) 5968429..5969421 + 993 WP_003195661.1 ABC transporter substrate-binding protein -
N2A98_RS26655 (N2A98_26680) 5969449..5970225 + 777 WP_032894483.1 ABC transporter permease -
N2A98_RS26660 (N2A98_26685) 5970222..5970989 + 768 WP_275622824.1 SDR family oxidoreductase -
N2A98_RS26665 (N2A98_26690) 5971003..5971542 + 540 WP_014720525.1 cupin domain-containing protein -
N2A98_RS26670 (N2A98_26695) 5971547..5972425 + 879 WP_275622825.1 alpha/beta hydrolase Toxin
N2A98_RS26675 (N2A98_26700) 5972422..5973255 + 834 WP_003195671.1 IclR family transcriptional regulator Antitoxin
N2A98_RS26680 (N2A98_26705) 5973257..5974054 + 798 WP_032894477.1 SDR family oxidoreductase -
N2A98_RS26685 (N2A98_26710) 5974047..5975732 + 1686 WP_047712100.1 thiamine pyrophosphate-binding protein -
N2A98_RS26690 (N2A98_26715) 5975743..5976546 + 804 WP_275622826.1 aspartate dehydrogenase -
N2A98_RS26695 (N2A98_26720) 5976556..5978052 + 1497 WP_275622827.1 aldehyde dehydrogenase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(45-276)

Antitoxin

(19-68)


Sequences


Toxin        


Download         Length: 293 a.a.        Molecular weight: 30762.22 Da        Isoelectric Point: 7.3823

>T257091 WP_275622825.1 NZ_CP104045:5971547-5972425 [Pseudomonas sp. FJ2-5-13]
MLPGLSQAAPTADLQALLERDFPQRLVASAGGQQALRECGAGPVVVLLHGIGSGAASWLQVARQLAPQARIIAWDAPGYG
DSSPLESDAPKAEQYAARLAQMLDALGVEECVLVGHSLGALTALAFARSSQAHRVNRLVLISPARGYGAPALGQQRQQVR
QQRLDNLQSLGIVGLAEQRSAHMLSPRATPQALAWVRWNMARLNPVGYRQAIELLCGDDLLRHGQPAMPCEVHCGEADSI
TPAEACLSVAKALGASFNLIADAGHASPIEQPQVVAGRLACAIHQSLTGRTL

Download         Length: 879 bp


Antitoxin


Download         Length: 278 a.a.        Molecular weight: 30601.10 Da        Isoelectric Point: 6.9636

>AT257091 WP_003195671.1 NZ_CP104045:5972422-5973255 [Pseudomonas sp. FJ2-5-13]
MNDSDLLKDAQDKYIVPGLERGLLLLCEFSRRNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRVNYPSNLVVRDGRSIVYVAKVSPPSVFSNAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSPCTPKTVMALFDLVQADRQRGFVSGEGFFESAISTVAAPVRDQSGGIVAALGVTIPTAQIGHVNF
EELLNQVRRSADELSRLLNYNGGAHNGQPRVTALMRD

Download         Length: 834 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References