Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | phd-doc/HTH_IclR(antitoxin) |
Location | 5971547..5973255 | Replicon | chromosome |
Accession | NZ_CP104045 | ||
Organism | Pseudomonas sp. FJ2-5-13 |
Toxin (Protein)
Gene name | doc | Uniprot ID | - |
Locus tag | N2A98_RS26670 | Protein ID | WP_275622825.1 |
Coordinates | 5971547..5972425 (+) | Length | 293 a.a. |
Antitoxin (Protein)
Gene name | phd | Uniprot ID | - |
Locus tag | N2A98_RS26675 | Protein ID | WP_003195671.1 |
Coordinates | 5972422..5973255 (+) | Length | 278 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
N2A98_RS26645 (N2A98_26670) | 5967553..5968389 | + | 837 | WP_050499539.1 | ABC transporter ATP-binding protein | - |
N2A98_RS26650 (N2A98_26675) | 5968429..5969421 | + | 993 | WP_003195661.1 | ABC transporter substrate-binding protein | - |
N2A98_RS26655 (N2A98_26680) | 5969449..5970225 | + | 777 | WP_032894483.1 | ABC transporter permease | - |
N2A98_RS26660 (N2A98_26685) | 5970222..5970989 | + | 768 | WP_275622824.1 | SDR family oxidoreductase | - |
N2A98_RS26665 (N2A98_26690) | 5971003..5971542 | + | 540 | WP_014720525.1 | cupin domain-containing protein | - |
N2A98_RS26670 (N2A98_26695) | 5971547..5972425 | + | 879 | WP_275622825.1 | alpha/beta hydrolase | Toxin |
N2A98_RS26675 (N2A98_26700) | 5972422..5973255 | + | 834 | WP_003195671.1 | IclR family transcriptional regulator | Antitoxin |
N2A98_RS26680 (N2A98_26705) | 5973257..5974054 | + | 798 | WP_032894477.1 | SDR family oxidoreductase | - |
N2A98_RS26685 (N2A98_26710) | 5974047..5975732 | + | 1686 | WP_047712100.1 | thiamine pyrophosphate-binding protein | - |
N2A98_RS26690 (N2A98_26715) | 5975743..5976546 | + | 804 | WP_275622826.1 | aspartate dehydrogenase | - |
N2A98_RS26695 (N2A98_26720) | 5976556..5978052 | + | 1497 | WP_275622827.1 | aldehyde dehydrogenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 293 a.a. Molecular weight: 30762.22 Da Isoelectric Point: 7.3823
>T257091 WP_275622825.1 NZ_CP104045:5971547-5972425 [Pseudomonas sp. FJ2-5-13]
MLPGLSQAAPTADLQALLERDFPQRLVASAGGQQALRECGAGPVVVLLHGIGSGAASWLQVARQLAPQARIIAWDAPGYG
DSSPLESDAPKAEQYAARLAQMLDALGVEECVLVGHSLGALTALAFARSSQAHRVNRLVLISPARGYGAPALGQQRQQVR
QQRLDNLQSLGIVGLAEQRSAHMLSPRATPQALAWVRWNMARLNPVGYRQAIELLCGDDLLRHGQPAMPCEVHCGEADSI
TPAEACLSVAKALGASFNLIADAGHASPIEQPQVVAGRLACAIHQSLTGRTL
MLPGLSQAAPTADLQALLERDFPQRLVASAGGQQALRECGAGPVVVLLHGIGSGAASWLQVARQLAPQARIIAWDAPGYG
DSSPLESDAPKAEQYAARLAQMLDALGVEECVLVGHSLGALTALAFARSSQAHRVNRLVLISPARGYGAPALGQQRQQVR
QQRLDNLQSLGIVGLAEQRSAHMLSPRATPQALAWVRWNMARLNPVGYRQAIELLCGDDLLRHGQPAMPCEVHCGEADSI
TPAEACLSVAKALGASFNLIADAGHASPIEQPQVVAGRLACAIHQSLTGRTL
Download Length: 879 bp
Antitoxin
Download Length: 278 a.a. Molecular weight: 30601.10 Da Isoelectric Point: 6.9636
>AT257091 WP_003195671.1 NZ_CP104045:5972422-5973255 [Pseudomonas sp. FJ2-5-13]
MNDSDLLKDAQDKYIVPGLERGLLLLCEFSRRNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRVNYPSNLVVRDGRSIVYVAKVSPPSVFSNAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSPCTPKTVMALFDLVQADRQRGFVSGEGFFESAISTVAAPVRDQSGGIVAALGVTIPTAQIGHVNF
EELLNQVRRSADELSRLLNYNGGAHNGQPRVTALMRD
MNDSDLLKDAQDKYIVPGLERGLLLLCEFSRRNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRVNYPSNLVVRDGRSIVYVAKVSPPSVFSNAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSPCTPKTVMALFDLVQADRQRGFVSGEGFFESAISTVAAPVRDQSGGIVAALGVTIPTAQIGHVNF
EELLNQVRRSADELSRLLNYNGGAHNGQPRVTALMRD
Download Length: 834 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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