Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 3881174..3882389 | Replicon | chromosome |
| Accession | NZ_CP104045 | ||
| Organism | Pseudomonas sp. FJ2-5-13 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | N2A98_RS16965 | Protein ID | WP_275622380.1 |
| Coordinates | 3881817..3882389 (+) | Length | 191 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | N2A98_RS16960 | Protein ID | WP_275622379.1 |
| Coordinates | 3881174..3881731 (+) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N2A98_RS16940 (N2A98_16960) | 3876926..3877558 | - | 633 | WP_275622375.1 | glutathione S-transferase | - |
| N2A98_RS16945 (N2A98_16965) | 3877775..3878851 | + | 1077 | WP_275622376.1 | aldo/keto reductase | - |
| N2A98_RS16950 (N2A98_16970) | 3879653..3880072 | - | 420 | WP_275622377.1 | chemotaxis protein CheY | - |
| N2A98_RS16955 (N2A98_16975) | 3880244..3881080 | + | 837 | WP_275622378.1 | HAD family acid phosphatase | - |
| N2A98_RS16960 (N2A98_16980) | 3881174..3881731 | + | 558 | WP_275622379.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| N2A98_RS16965 (N2A98_16985) | 3881817..3882389 | + | 573 | WP_275622380.1 | HD domain-containing protein | Toxin |
| N2A98_RS16970 (N2A98_16990) | 3882399..3882821 | - | 423 | WP_072446228.1 | RidA family protein | - |
| N2A98_RS16975 (N2A98_16995) | 3882833..3884416 | - | 1584 | WP_275622381.1 | FAD-dependent oxidoreductase | - |
| N2A98_RS16980 (N2A98_17000) | 3884429..3885352 | - | 924 | WP_047711275.1 | ABC transporter substrate-binding protein | - |
| N2A98_RS16985 (N2A98_17005) | 3885371..3886144 | - | 774 | WP_047711276.1 | amino acid ABC transporter ATP-binding protein | - |
| N2A98_RS16990 (N2A98_17010) | 3886137..3887108 | - | 972 | WP_275622382.1 | amino acid ABC transporter permease | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 191 a.a. Molecular weight: 21303.41 Da Isoelectric Point: 5.1128
>T257090 WP_275622380.1 NZ_CP104045:3881817-3882389 [Pseudomonas sp. FJ2-5-13]
MDMEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAIHGDIP
AVSQAAFPNKGEQERRDLLLLAQSLDSPLKAEILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAQPLFEALRALIDQATEQRLHAAE
MDMEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAIHGDIP
AVSQAAFPNKGEQERRDLLLLAQSLDSPLKAEILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAQPLFEALRALIDQATEQRLHAAE
Download Length: 573 bp
Antitoxin
Download Length: 186 a.a. Molecular weight: 20492.49 Da Isoelectric Point: 8.8351
>AT257090 WP_275622379.1 NZ_CP104045:3881174-3881731 [Pseudomonas sp. FJ2-5-13]
MTHSLLKPALPGIALRRWRLLHRIKQSHAAQLFNVTQSTVSRWESGVQAMDPAAHQQLEQLLAARLDAAADQALARLVSE
SSQAMHLVCDLTHRLLACSPSRARQFSSPLAELMGQSLWRFATPQIQLIEASLEHTGWRETQAPPALEFATGSNDSNLVP
IRPSICRWTRMTLSDGSAARLVETL
MTHSLLKPALPGIALRRWRLLHRIKQSHAAQLFNVTQSTVSRWESGVQAMDPAAHQQLEQLLAARLDAAADQALARLVSE
SSQAMHLVCDLTHRLLACSPSRARQFSSPLAELMGQSLWRFATPQIQLIEASLEHTGWRETQAPPALEFATGSNDSNLVP
IRPSICRWTRMTLSDGSAARLVETL
Download Length: 558 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|