Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 297815..298617 Replicon plasmid pWSM4643_1
Accession NZ_CP104041
Organism Rhizobium leguminosarum bv. viciae strain WSM4643

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag N1937_RS25310 Protein ID WP_260059686.1
Coordinates 298090..298617 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag N1937_RS25305 Protein ID WP_170280972.1
Coordinates 297815..298093 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N1937_RS25285 (N1937_25285) 293041..294561 - 1521 WP_260059684.1 ABC transporter substrate-binding protein -
N1937_RS25290 (N1937_25290) 294775..295560 + 786 WP_170255606.1 IclR family transcriptional regulator -
N1937_RS25295 (N1937_25295) 295631..296353 + 723 WP_017967670.1 ribonuclease activity regulator RraA -
N1937_RS25300 (N1937_25300) 296780..297610 + 831 WP_260059706.1 DUF6030 family protein -
N1937_RS25305 (N1937_25305) 297815..298093 + 279 WP_170280972.1 DUF1778 domain-containing protein Antitoxin
N1937_RS25310 (N1937_25310) 298090..298617 + 528 WP_260059686.1 GNAT family N-acetyltransferase Toxin
N1937_RS25315 (N1937_25315) 298764..299108 - 345 WP_260059687.1 hypothetical protein -
N1937_RS25320 (N1937_25320) 299496..300017 + 522 WP_026154513.1 tetratricopeptide repeat protein -
N1937_RS25325 (N1937_25325) 300229..300789 - 561 WP_260059688.1 hypothetical protein -
N1937_RS25330 (N1937_25330) 300869..302173 - 1305 WP_260059689.1 AAA family ATPase -
N1937_RS25335 (N1937_25335) 302188..303129 - 942 WP_222385901.1 type II secretion system F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..627412 627412


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(12-87)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18706.71 Da        Isoelectric Point: 8.8575

>T257079 WP_260059686.1 NZ_CP104041:298090-298617 [Rhizobium leguminosarum bv. viciae]
VTLPVWHEEPIAKSHDRAAFDCGDAAMNEFIRRFARQSHEQNAAKTFCAIDKAQPDCILGFYTVAPSAVTHEAVPPKMTR
GLARHEVAGFKLARLATDIKVAGKGLGGQLIAAAALRCLRLASEGGGILLIIDAKSERAAHWYAGYGAEPLQGKPLTLVM
PLATFAADFKAKGLL

Download         Length: 528 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10132.82 Da        Isoelectric Point: 8.6184

>AT257079 WP_170280972.1 NZ_CP104041:297815-298093 [Rhizobium leguminosarum bv. viciae]
MPRTADSKTERYQLRIPPKQKAMIARAAALSNKDMADFILDKIVPEAEAVIQAAEVEAVSSRDFIRILDLLEHPPKPNAK
LRAAISALPDAL

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References