Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 109885..110420 Replicon plasmid pSRDI969_2
Accession NZ_CP104037
Organism Rhizobium leguminosarum bv. viciae strain SRDI969

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag N2A41_RS27680 Protein ID WP_170256924.1
Coordinates 110130..110420 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag N2A41_RS27675 Protein ID WP_260111697.1
Coordinates 109885..110133 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2A41_RS27660 (N2A41_27660) 105467..107176 + 1710 WP_260111695.1 ABC transporter ATP-binding protein -
N2A41_RS27665 (N2A41_27665) 107196..108710 + 1515 WP_222386008.1 ABC transporter substrate-binding protein -
N2A41_RS27670 (N2A41_27670) 108795..109670 - 876 WP_260111696.1 glutathione-dependent disulfide-bond oxidoreductase -
N2A41_RS27675 (N2A41_27675) 109885..110133 + 249 WP_260111697.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
N2A41_RS27680 (N2A41_27680) 110130..110420 + 291 WP_170256924.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N2A41_RS27685 (N2A41_27685) 110432..111283 - 852 WP_260111698.1 NAD(P)-dependent oxidoreductase -
N2A41_RS27690 (N2A41_27690) 111495..111962 + 468 WP_260111699.1 universal stress protein -
N2A41_RS27695 (N2A41_27695) 112080..112994 + 915 WP_260111700.1 J domain-containing protein -
N2A41_RS27700 (N2A41_27700) 112997..113320 + 324 WP_260060111.1 chaperone modulator CbpM -
N2A41_RS27705 (N2A41_27705) 113335..114264 - 930 WP_260111701.1 phosphatidate cytidylyltransferase -
N2A41_RS27710 (N2A41_27710) 114261..114881 - 621 WP_017969181.1 lysophospholipid acyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd 1..548849 548849


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11089.51 Da        Isoelectric Point: 6.7147

>T257074 WP_170256924.1 NZ_CP104037:110130-110420 [Rhizobium leguminosarum bv. viciae]
MTDIIFSPAAQTDIDKIWDYTATSWNVDQAERYVQDIRDACQDLAEGTRMSRPSDIRKGYRKVSVGSHFLYFQSNDAGQI
IIVRILHQRMDVAKHL

Download         Length: 291 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8929.00 Da        Isoelectric Point: 6.4652

>AT257074 WP_260111697.1 NZ_CP104037:109885-110133 [Rhizobium leguminosarum bv. viciae]
MARSTSISLGEHFTSFIDTQVQAGRYGSATDVVRAGLRLLEEHEAKVKALQDALIEGEESGPATPFDFDAFNARKRAAFK
AK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References