Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 287360..288162 Replicon plasmid pSRDI969_1
Accession NZ_CP104036
Organism Rhizobium leguminosarum bv. viciae strain SRDI969

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag N2A41_RS25530 Protein ID WP_222385899.1
Coordinates 287635..288162 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag N2A41_RS25525 Protein ID WP_164577378.1
Coordinates 287360..287638 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2A41_RS25505 (N2A41_25505) 282591..284111 - 1521 WP_170259487.1 ABC transporter substrate-binding protein -
N2A41_RS25510 (N2A41_25510) 284325..285110 + 786 WP_222385897.1 IclR family transcriptional regulator -
N2A41_RS25515 (N2A41_25515) 285181..285903 + 723 WP_017967670.1 ribonuclease activity regulator RraA -
N2A41_RS25520 (N2A41_25520) 286330..287160 + 831 WP_260111439.1 DUF6030 family protein -
N2A41_RS25525 (N2A41_25525) 287360..287638 + 279 WP_164577378.1 DUF1778 domain-containing protein Antitoxin
N2A41_RS25530 (N2A41_25530) 287635..288162 + 528 WP_222385899.1 GNAT family N-acetyltransferase Toxin
N2A41_RS25535 (N2A41_25535) 289040..289561 + 522 WP_026154513.1 tetratricopeptide repeat protein -
N2A41_RS25540 (N2A41_25540) 289676..290236 - 561 WP_260111408.1 hypothetical protein -
N2A41_RS25545 (N2A41_25545) 290316..291620 - 1305 WP_260111409.1 AAA family ATPase -
N2A41_RS25550 (N2A41_25550) 291636..292580 - 945 WP_260111410.1 type II secretion system F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..637289 637289


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(12-87)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18763.76 Da        Isoelectric Point: 8.8575

>T257073 WP_222385899.1 NZ_CP104036:287635-288162 [Rhizobium leguminosarum bv. viciae]
VTLPVWHEEPIAKSHDRAAFDCGDAAMNEFIRRLARQSHEQNAAKTFCAIDKAQPDCILGFYTVAPSAVTHEAVPPKMTR
GLARHEVAGFKLARLATDIKVAGKGLGGQFIAAAALRCLRLASEGGGILLIIDTKNERAAHWYAGYGAEPLQGKPLTLVM
PLATFAADFKAKGLL

Download         Length: 528 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10162.85 Da        Isoelectric Point: 8.6184

>AT257073 WP_164577378.1 NZ_CP104036:287360-287638 [Rhizobium leguminosarum bv. viciae]
MPRTADSKTERYQLRIPPKQKAMIARAAALSNKDMADFILDKIVPEAEAVIQAAEVETVSSRDFIRILDLLEHPPKPNAK
LRAAISALPDAL

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References