Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3042883..3043549 Replicon chromosome
Accession NZ_CP104025
Organism Erwinia amylovora strain Ea915

Toxin (Protein)


Gene name cptA Uniprot ID A0A830ZTB8
Locus tag MTP51_RS13810 Protein ID WP_004161808.1
Coordinates 3042883..3043302 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID D4HWC2
Locus tag MTP51_RS13815 Protein ID WP_004155593.1
Coordinates 3043283..3043549 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTP51_RS13795 (MTP51_13795) 3038875..3040554 + 1680 WP_004155599.1 type III effector -
MTP51_RS13800 (MTP51_13800) 3041064..3042017 + 954 WP_004155597.1 DMT family transporter -
MTP51_RS13805 (MTP51_13805) 3042247..3042765 + 519 WP_004155596.1 flavodoxin FldB -
MTP51_RS13810 (MTP51_13810) 3042883..3043302 - 420 WP_004161808.1 protein YgfX Toxin
MTP51_RS13815 (MTP51_13815) 3043283..3043549 - 267 WP_004155593.1 FAD assembly factor SdhE Antitoxin
MTP51_RS13820 (MTP51_13820) 3043775..3044761 + 987 WP_004155590.1 tRNA-modifying protein YgfZ -
MTP51_RS13825 (MTP51_13825) 3044762..3045421 - 660 WP_004155588.1 hemolysin III family protein -
MTP51_RS13830 (MTP51_13830) 3045634..3046242 + 609 WP_004155587.1 HD domain-containing protein -
MTP51_RS13835 (MTP51_13835) 3046347..3047076 - 730 Protein_2658 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16366.46 Da        Isoelectric Point: 11.9444

>T257039 WP_004161808.1 NZ_CP104025:c3043302-3042883 [Erwinia amylovora]
VVLWQCELRPSRLAQRFSLLLHGAVMLALLLPTWPASSGLVRMLLLVLVLLECIRSRRRIGRRQGDIALLEGHELRWRQR
EWCIISRPWLTGQAILLLLQDTHGQRERLWLFADGMEKRNWRQLRLQLLNSKVQGNGWC

Download         Length: 420 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10498.07 Da        Isoelectric Point: 6.4605

>AT257039 WP_004155593.1 NZ_CP104025:c3043549-3043283 [Erwinia amylovora]
MDITNKSRIHWACRRGMRELDISIMPFFQYEFDSLNDSDKRLFVRLLESDDPDLFNWLMNHGEPADVELKRMVALIQQRN
KQRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A830ZTB8

Antitoxin

Source ID Structure
AlphaFold DB A0A831A3F0

References