Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 897567..898020 Replicon chromosome
Accession NZ_CP104025
Organism Erwinia amylovora strain Ea915

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MTP51_RS03930 Protein ID WP_013035888.1
Coordinates 897784..898020 (+) Length 79 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID D4HZA2
Locus tag MTP51_RS03925 Protein ID WP_004159527.1
Coordinates 897567..897794 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTP51_RS03915 (MTP51_03915) 896491..896895 + 405 WP_013035886.1 hypothetical protein -
MTP51_RS03920 (MTP51_03920) 896959..897246 - 288 WP_264072243.1 type I toxin-antitoxin system SymE family toxin -
MTP51_RS03925 (MTP51_03925) 897567..897794 + 228 WP_004159527.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MTP51_RS03930 (MTP51_03930) 897784..898020 + 237 WP_013035888.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MTP51_RS03935 (MTP51_03935) 898007..898225 - 219 WP_004159522.1 hypothetical protein -
MTP51_RS03940 (MTP51_03940) 898553..900769 + 2217 Protein_747 ferrichrome porin FhuA -
MTP51_RS03945 (MTP51_03945) 900818..901612 + 795 WP_004159512.1 Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC -
MTP51_RS03950 (MTP51_03950) 901627..902505 + 879 WP_004159509.1 Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-78)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-75)


Sequences

Toxin        


Download         Length: 79 a.a.        Molecular weight: 9135.79 Da        Isoelectric Point: 9.0876

>T257035 WP_013035888.1 NZ_CP104025:897784-898020 [Erwinia amylovora]
ISYELLFDPWALKEWKKLGATVREQFKKKLAEVLVNLQVESARLRDHPDCCKIKLKSSGYRLVYQVQDEQLVMLVISV

Download         Length: 237 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8435.90 Da        Isoelectric Point: 7.9766

>AT257035 WP_004159527.1 NZ_CP104025:897567-897794 [Erwinia amylovora]
VRLDDKLKSKACAVLDELDVSPTEAVRLLFQYIAENERLPLKALTVSDEKDALLKTVRERLASLQKGIKVTLDKL

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A831A410

References