Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 897564..898017 Replicon chromosome
Accession NZ_CP104022
Organism Erwinia amylovora strain Ea102

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MTP49_RS03925 Protein ID WP_013035888.1
Coordinates 897781..898017 (+) Length 79 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID D4HZA2
Locus tag MTP49_RS03920 Protein ID WP_004159527.1
Coordinates 897564..897791 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTP49_RS03910 (MTP49_03910) 896488..896892 + 405 WP_013035886.1 hypothetical protein -
MTP49_RS03915 (MTP49_03915) 896956..897243 - 288 WP_264072243.1 type I toxin-antitoxin system SymE family toxin -
MTP49_RS03920 (MTP49_03920) 897564..897791 + 228 WP_004159527.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MTP49_RS03925 (MTP49_03925) 897781..898017 + 237 WP_013035888.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MTP49_RS03930 (MTP49_03930) 898004..898222 - 219 WP_004159522.1 hypothetical protein -
MTP49_RS03935 (MTP49_03935) 898550..900766 + 2217 Protein_746 ferrichrome porin FhuA -
MTP49_RS03940 (MTP49_03940) 900815..901609 + 795 WP_004159512.1 Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC -
MTP49_RS03945 (MTP49_03945) 901624..902502 + 879 WP_004159509.1 Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-78)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-75)


Sequences

Toxin        


Download         Length: 79 a.a.        Molecular weight: 9135.79 Da        Isoelectric Point: 9.0876

>T257026 WP_013035888.1 NZ_CP104022:897781-898017 [Erwinia amylovora]
ISYELLFDPWALKEWKKLGATVREQFKKKLAEVLVNLQVESARLRDHPDCCKIKLKSSGYRLVYQVQDEQLVMLVISV

Download         Length: 237 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8435.90 Da        Isoelectric Point: 7.9766

>AT257026 WP_004159527.1 NZ_CP104022:897564-897791 [Erwinia amylovora]
VRLDDKLKSKACAVLDELDVSPTEAVRLLFQYIAENERLPLKALTVSDEKDALLKTVRERLASLQKGIKVTLDKL

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A831A410

References