Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3838726..3839383 Replicon chromosome
Accession NZ_CP104014
Organism Enterobacter sp. CP102

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag N1249_RS18040 Protein ID WP_014071653.1
Coordinates 3838726..3839136 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A198H1V0
Locus tag N1249_RS18045 Protein ID WP_014071654.1
Coordinates 3839117..3839383 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N1249_RS18020 (N1249_18020) 3834720..3836453 - 1734 WP_259831844.1 single-stranded-DNA-specific exonuclease RecJ -
N1249_RS18025 (N1249_18025) 3836459..3837172 - 714 WP_014071650.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
N1249_RS18030 (N1249_18030) 3837201..3838097 - 897 WP_259831845.1 site-specific tyrosine recombinase XerD -
N1249_RS18035 (N1249_18035) 3838199..3838720 + 522 WP_259831846.1 flavodoxin FldB -
N1249_RS18040 (N1249_18040) 3838726..3839136 - 411 WP_014071653.1 protein YgfX Toxin
N1249_RS18045 (N1249_18045) 3839117..3839383 - 267 WP_014071654.1 FAD assembly factor SdhE Antitoxin
N1249_RS18050 (N1249_18050) 3839677..3840657 + 981 WP_259831847.1 tRNA-modifying protein YgfZ -
N1249_RS18055 (N1249_18055) 3840725..3841384 - 660 WP_014071656.1 hemolysin III family protein -
N1249_RS18060 (N1249_18060) 3841550..3841861 - 312 WP_182062341.1 N(4)-acetylcytidine aminohydrolase -
N1249_RS18065 (N1249_18065) 3841914..3842645 + 732 WP_014071659.1 MurR/RpiR family transcriptional regulator -
N1249_RS18070 (N1249_18070) 3842762..3844195 + 1434 WP_259831848.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16191.12 Da        Isoelectric Point: 11.5436

>T257008 WP_014071653.1 NZ_CP104014:c3839136-3838726 [Enterobacter sp. CP102]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLMMDSRLRWQGK
EWEIIGTPWMLSSGMMLRLRKVGGGRRQHLWLAADSMDEVEWRDLRRMVLQQPTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10569.05 Da        Isoelectric Point: 5.1456

>AT257008 WP_014071654.1 NZ_CP104014:c3839383-3839117 [Enterobacter sp. CP102]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSEDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A198H1V0

References