Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 573109..573547 Replicon chromosome
Accession NZ_CP104014
Organism Enterobacter sp. CP102

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag N1249_RS02715 Protein ID WP_259834326.1
Coordinates 573109..573258 (+) Length 50 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag N1249_RS02720 Protein ID WP_259834328.1
Coordinates 573245..573547 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N1249_RS02700 (N1249_02700) 569562..570569 + 1008 WP_259834320.1 hypothetical protein -
N1249_RS02705 (N1249_02705) 570566..571654 + 1089 WP_259834322.1 glycoside hydrolase family 88 protein -
N1249_RS02710 (N1249_02710) 571666..572937 - 1272 WP_259834324.1 DUF445 domain-containing protein -
N1249_RS02715 (N1249_02715) 573109..573258 + 150 WP_259834326.1 hypothetical protein Toxin
N1249_RS02720 (N1249_02720) 573245..573547 + 303 WP_259834328.1 BrnA antitoxin family protein Antitoxin
N1249_RS02725 (N1249_02725) 573583..574221 - 639 WP_259834330.1 LysE family translocator -
N1249_RS02730 (N1249_02730) 574269..575012 - 744 WP_259834331.1 AraC family transcriptional regulator -
N1249_RS02735 (N1249_02735) 575192..575737 - 546 WP_259834332.1 YfaZ family protein -
N1249_RS02740 (N1249_02740) 576225..576359 - 135 WP_259834333.1 hypothetical protein -
N1249_RS02745 (N1249_02745) 576374..576559 - 186 WP_259834336.1 SymE family type I addiction module toxin -
N1249_RS02750 (N1249_02750) 576787..578139 - 1353 WP_259834337.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(34-93)


Sequences

Toxin        


Download         Length: 50 a.a.        Molecular weight: 5835.58 Da        Isoelectric Point: 10.3582

>T257000 WP_259834326.1 NZ_CP104014:573109-573258 [Enterobacter sp. CP102]
MPTEFEWNSSKAKSNLQKHGIRFESGNEIIRIISARKADRKERSRYEHC

Download         Length: 150 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11447.10 Da        Isoelectric Point: 9.4865

>AT257000 WP_259834328.1 NZ_CP104014:573245-573547 [Enterobacter sp. CP102]
MSIVKHKRGSAAEVSVHREAELHALAEKPDAEIDYSDIPAMDEALWNDAVRGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References