Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | slvAT/RES(toxin) |
| Location | 734860..735755 | Replicon | chromosome |
| Accession | NC_016147 | ||
| Organism | Pseudoxanthomonas spadix BD-a59 | ||
Toxin (Protein)
| Gene name | slvT | Uniprot ID | G7UPA6 |
| Locus tag | DSC_RS03275 | Protein ID | WP_014159703.1 |
| Coordinates | 734860..735387 (-) | Length | 176 a.a. |
Antitoxin (Protein)
| Gene name | slvA | Uniprot ID | G7UPA7 |
| Locus tag | DSC_RS03280 | Protein ID | WP_014159704.1 |
| Coordinates | 735384..735755 (-) | Length | 124 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DSC_RS16985 | 730579..730722 | + | 144 | Protein_666 | IS1595 family transposase | - |
| DSC_RS03260 | 730810..731265 | - | 456 | WP_014159699.1 | Cu(I)-responsive transcriptional regulator | - |
| DSC_RS03265 | 731240..733696 | - | 2457 | WP_202944911.1 | heavy metal translocating P-type ATPase | - |
| DSC_RS03270 | 733882..734118 | + | 237 | WP_014159701.1 | cation transporter | - |
| DSC_RS15955 | 734495..734674 | - | 180 | Protein_670 | DUF1845 family protein | - |
| DSC_RS03275 | 734860..735387 | - | 528 | WP_014159703.1 | RES family NAD+ phosphorylase | Toxin |
| DSC_RS03280 | 735384..735755 | - | 372 | WP_014159704.1 | hypothetical protein | Antitoxin |
| DSC_RS03285 | 736205..737266 | - | 1062 | WP_014159705.1 | alcohol dehydrogenase | - |
| DSC_RS03290 | 737290..738351 | - | 1062 | WP_014159706.1 | 2Fe-2S iron-sulfur cluster binding domain-containing protein | - |
| DSC_RS03295 | 738412..739398 | - | 987 | WP_014159707.1 | aromatic/alkene monooxygenase hydroxylase subunit beta | - |
| DSC_RS03300 | 739453..739770 | - | 318 | WP_014159708.1 | MmoB/DmpM family protein | - |
| DSC_RS03305 | 739801..740136 | - | 336 | WP_014159709.1 | Rieske 2Fe-2S domain-containing protein | - |
| DSC_RS03310 | 740149..740415 | - | 267 | WP_014159710.1 | toluene-4-monooxygenase system B family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 734189..760660 | 26471 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 176 a.a. Molecular weight: 19739.14 Da Isoelectric Point: 5.5222
>T25700 WP_014159703.1 NC_016147:c735387-734860 [Pseudoxanthomonas spadix BD-a59]
VILLDLPPGATLFRAHTPQWASRPTSGAGAAAKGGRFNREGVEALYLSLEEVTALREYQQTSPFLPPCTMCSYTANLRGL
VDLRQLHHGEPWDELWHDWREDWRHLKFDLHIEPPTWVLGDMVLAQGHTGILFPSQANDGGTNVMVFVDRLRDGNSVEVN
DPDGRLPRDQSSWTR
VILLDLPPGATLFRAHTPQWASRPTSGAGAAAKGGRFNREGVEALYLSLEEVTALREYQQTSPFLPPCTMCSYTANLRGL
VDLRQLHHGEPWDELWHDWREDWRHLKFDLHIEPPTWVLGDMVLAQGHTGILFPSQANDGGTNVMVFVDRLRDGNSVEVN
DPDGRLPRDQSSWTR
Download Length: 528 bp
>T25700 NC_016147:c735387-734860 [Pseudoxanthomonas spadix BD-a59]
GTGATCCTCCTCGACCTGCCGCCCGGCGCCACGCTGTTTCGTGCGCACACTCCACAGTGGGCCAGCCGGCCCACCAGTGG
TGCCGGTGCAGCGGCCAAGGGCGGTCGCTTCAATCGAGAAGGCGTCGAGGCGCTGTATCTATCACTGGAGGAAGTGACCG
CGTTACGCGAGTACCAGCAGACCTCGCCCTTCCTGCCGCCCTGCACGATGTGCTCGTATACCGCGAACTTGCGCGGACTG
GTCGATCTGCGGCAGCTCCACCACGGCGAGCCCTGGGACGAGCTGTGGCACGACTGGCGCGAGGACTGGCGCCACCTGAA
ATTCGACCTTCACATCGAGCCGCCCACCTGGGTGCTGGGCGACATGGTGCTGGCCCAGGGCCACACAGGCATCCTGTTCC
CCAGCCAGGCGAACGATGGCGGCACCAATGTCATGGTGTTCGTGGATAGGCTCAGAGATGGCAATTCGGTCGAGGTCAAT
GATCCCGACGGGCGACTGCCCCGCGACCAATCCAGTTGGACGCGCTGA
GTGATCCTCCTCGACCTGCCGCCCGGCGCCACGCTGTTTCGTGCGCACACTCCACAGTGGGCCAGCCGGCCCACCAGTGG
TGCCGGTGCAGCGGCCAAGGGCGGTCGCTTCAATCGAGAAGGCGTCGAGGCGCTGTATCTATCACTGGAGGAAGTGACCG
CGTTACGCGAGTACCAGCAGACCTCGCCCTTCCTGCCGCCCTGCACGATGTGCTCGTATACCGCGAACTTGCGCGGACTG
GTCGATCTGCGGCAGCTCCACCACGGCGAGCCCTGGGACGAGCTGTGGCACGACTGGCGCGAGGACTGGCGCCACCTGAA
ATTCGACCTTCACATCGAGCCGCCCACCTGGGTGCTGGGCGACATGGTGCTGGCCCAGGGCCACACAGGCATCCTGTTCC
CCAGCCAGGCGAACGATGGCGGCACCAATGTCATGGTGTTCGTGGATAGGCTCAGAGATGGCAATTCGGTCGAGGTCAAT
GATCCCGACGGGCGACTGCCCCGCGACCAATCCAGTTGGACGCGCTGA
Antitoxin
Download Length: 124 a.a. Molecular weight: 13412.18 Da Isoelectric Point: 6.0723
>AT25700 WP_014159704.1 NC_016147:c735755-735384 [Pseudoxanthomonas spadix BD-a59]
MVSTAFADVLESVREAGTSRFSATNVADALGLQYQDLATLAGVHRNTLRTHPESPRLQAALRELMRVLSAATVVQPDTAR
AFFMVKNEPIPAFHHKTLLQLVQEGRTDDAIDYLESISAGFTG
MVSTAFADVLESVREAGTSRFSATNVADALGLQYQDLATLAGVHRNTLRTHPESPRLQAALRELMRVLSAATVVQPDTAR
AFFMVKNEPIPAFHHKTLLQLVQEGRTDDAIDYLESISAGFTG
Download Length: 372 bp
>AT25700 NC_016147:c735755-735384 [Pseudoxanthomonas spadix BD-a59]
ATGGTCTCTACCGCTTTCGCAGATGTGCTCGAGTCGGTGCGTGAGGCCGGCACGTCCCGCTTTTCCGCCACGAACGTCGC
CGATGCCCTGGGCCTGCAGTACCAGGATCTGGCCACCCTGGCCGGGGTGCACCGCAACACCCTGCGCACCCATCCCGAAT
CCCCGCGACTGCAGGCCGCGCTGCGTGAGCTGATGCGCGTGCTGTCGGCCGCCACGGTGGTGCAGCCGGATACCGCGCGT
GCGTTCTTCATGGTCAAGAACGAACCCATTCCGGCGTTCCACCACAAGACCCTGCTGCAGTTGGTGCAGGAAGGACGCAC
CGACGATGCGATCGACTACCTGGAGTCGATCAGTGCAGGGTTCACCGGGTGA
ATGGTCTCTACCGCTTTCGCAGATGTGCTCGAGTCGGTGCGTGAGGCCGGCACGTCCCGCTTTTCCGCCACGAACGTCGC
CGATGCCCTGGGCCTGCAGTACCAGGATCTGGCCACCCTGGCCGGGGTGCACCGCAACACCCTGCGCACCCATCCCGAAT
CCCCGCGACTGCAGGCCGCGCTGCGTGAGCTGATGCGCGTGCTGTCGGCCGCCACGGTGGTGCAGCCGGATACCGCGCGT
GCGTTCTTCATGGTCAAGAACGAACCCATTCCGGCGTTCCACCACAAGACCCTGCTGCAGTTGGTGCAGGAAGGACGCAC
CGACGATGCGATCGACTACCTGGAGTCGATCAGTGCAGGGTTCACCGGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|