Detailed information of TA system TA256998

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 3477716..3478849
• Replicon: chromosome
• Accession: NZ_CP104011
• Organism: Pseudomonas sp. GCEP-101 isolate Gut

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: N0B71_RS16025
• Protein ID: WP_259753531.1
• Coordinates: 3478085..3478849 (+)
• Length: 255 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: N0B71_RS16020
• Protein ID: WP_259753529.1
• Coordinates: 3477716..3478084 (+)
• Length: 123 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N0B71_RS15980	3473262..3474020	+	759	WP_259753522.1	MBL fold metallo-hydrolase	-
N0B71_RS15985	3474050..3474760	+	711	WP_038803299.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
N0B71_RS15995	3475032..3475403	-	372	WP_259753523.1	hypothetical protein	-
N0B71_RS16000	3475501..3475848	-	348	WP_017522075.1	carboxymuconolactone decarboxylase family protein	-
N0B71_RS16005	3475978..3476460	-	483	WP_259753524.1	GreA/GreB family elongation factor	-
N0B71_RS16010	3476585..3477016	+	432	WP_259753526.1	hypothetical protein	-
N0B71_RS16015	3477023..3477463	-	441	WP_259753527.1	RcnB family protein	-
N0B71_RS16020	3477716..3478084	+	369	WP_259753529.1	DUF2384 domain-containing protein	Antitoxin
N0B71_RS16025	3478085..3478849	+	765	WP_259753531.1	RES family NAD+ phosphorylase	Toxin
N0B71_RS16030	3478926..3479135	+	210	WP_259753533.1	hypothetical protein	-
N0B71_RS16035	3479695..3481059	+	1365	WP_259759584.1	DNA recombination protein RmuC	-
N0B71_RS16040	3481376..3482722	-	1347	WP_259753535.1	FAD-binding oxidoreductase	-
N0B71_RS16045	3482811..3483701	-	891	WP_259753537.1	metal-dependent hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (68-210)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (71-120)

Sequences

Toxin

Protein

• Length: 255 a.a.
• Molecular weight: 28824.04 Da
• Isoelectric Point: 8.8850

>T256998 WP_259753531.1 NZ_CP104011:3478085-3478849 [Pseudomonas sp. GCEP-101]
MSFAAGARLWANYEDSVVAPMRGRLVRLVESQGQVATLQLVDTLEEQALLEELLETSKPRMPPPAEPLHYLLKTPFRYPP
LRWGSRFGRRHEPSLFYGALKLETAMAESAFYRFVLWEGMATPPPSGRILSEHASFEARFQVQKGVRLHLPPFREHAALT
DPQDYSVTQGLGSAMREAGIEAFEYRSARCPQGGINVALFVPSAFTEKRPRNLMPWLCETTAEYVAFKHAQVPDSPRLYR
REQYLVNGRLPHPA

Nucleotide

• Length: 765 bp

Antitoxin

Protein

• Length: 123 a.a.
• Molecular weight: 13431.66 Da
• Isoelectric Point: 9.0715

>AT256998 WP_259753529.1 NZ_CP104011:3477716-3478084 [Pseudomonas sp. GCEP-101]
MSALLRENPAADAVLAKAVLTAREHLAMTQQQLAAIVGVDRSAVSRWKQNGLRVDSKTGELALLLVRIYRALFALFGGNH
EDMRHFLCTENRHLGGVPLQLMEQVQGLVAVVEYLDAIRGKV

Nucleotide

• Length: 369 bp