Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 3152880..3153488 Replicon chromosome
Accession NZ_CP104011
Organism Pseudomonas sp. GCEP-101 isolate Gut

Toxin (Protein)


Gene name PfiT Uniprot ID -
Locus tag N0B71_RS14440 Protein ID WP_259753256.1
Coordinates 3153141..3153488 (+) Length 116 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID -
Locus tag N0B71_RS14435 Protein ID WP_259753255.1
Coordinates 3152880..3153131 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0B71_RS14410 3148103..3148741 - 639 WP_259753250.1 ferric reductase-like transmembrane domain-containing protein -
N0B71_RS14415 3148866..3150176 - 1311 WP_259753251.1 HAMP domain-containing sensor histidine kinase -
N0B71_RS14420 3150173..3150913 - 741 WP_259753252.1 response regulator -
N0B71_RS14425 3151140..3151412 + 273 WP_259753253.1 DUF2790 domain-containing protein -
N0B71_RS14430 3151506..3152726 + 1221 WP_259753254.1 cytochrome c biogenesis protein DipZ -
N0B71_RS14435 3152880..3153131 + 252 WP_259753255.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N0B71_RS14440 3153141..3153488 + 348 WP_259753256.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N0B71_RS14445 3153493..3155340 - 1848 WP_259753257.1 sensor domain-containing diguanylate cyclase -
N0B71_RS14450 3155611..3156681 - 1071 WP_259753258.1 serine/threonine-protein kinase -
N0B71_RS14455 3156681..3157736 - 1056 WP_259753259.1 serine/threonine-protein kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-100)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 13202.18 Da        Isoelectric Point: 6.2124

>T256997 WP_259753256.1 NZ_CP104011:3153141-3153488 [Pseudomonas sp. GCEP-101]
VSRLVVRFTHTAEQSIQDQVHHLVPFLGQQNALDSLLELIVEIEEKLPRAPAGYPVSEQASLLGVLHFREFNTGPYRVFY
EVHEHLSEIAVILVLRQKQSVQQQLIRYCLVGPFE

Download         Length: 348 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9294.55 Da        Isoelectric Point: 7.2004

>AT256997 WP_259753255.1 NZ_CP104011:3152880-3153131 [Pseudomonas sp. GCEP-101]
MRVETISYLKRHAADLDLTEPMVVTQNGVPAYVVESYAERQQRDEAIALVKLLAMGSRQYAEGKHSSADDLKARLAKRFS
PSD

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References