Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 940510..941174 Replicon chromosome
Accession NZ_CP104011
Organism Pseudomonas sp. GCEP-101 isolate Gut

Toxin (Protein)


Gene name VapC1 Uniprot ID -
Locus tag N0B71_RS04355 Protein ID WP_259757474.1
Coordinates 940767..941174 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag N0B71_RS04350 Protein ID WP_259757473.1
Coordinates 940510..940770 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0B71_RS04335 937097..937873 - 777 WP_259757469.1 ferredoxin--NADP reductase -
N0B71_RS04340 937980..938972 - 993 WP_259757471.1 TRAP transporter substrate-binding protein -
N0B71_RS04345 939309..940433 + 1125 WP_259757472.1 class I SAM-dependent methyltransferase -
N0B71_RS04350 940510..940770 + 261 WP_259757473.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
N0B71_RS04355 940767..941174 + 408 WP_259757474.1 type II toxin-antitoxin system VapC family toxin Toxin
N0B71_RS04360 941244..942101 + 858 WP_259757475.1 alpha/beta hydrolase -
N0B71_RS04365 942191..942757 - 567 WP_259757476.1 nucleotidyltransferase family protein -
N0B71_RS04370 942754..943725 - 972 WP_259757477.1 XdhC family protein -
N0B71_RS04375 943729..944940 - 1212 WP_259757478.1 cytochrome c -
N0B71_RS04380 944943..945482 - 540 WP_259757479.1 (2Fe-2S)-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-127)

Antitoxin

SpoVT-AbrB domain

(11-46)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15300.57 Da        Isoelectric Point: 7.3211

>T256993 WP_259757474.1 NZ_CP104011:940767-941174 [Pseudomonas sp. GCEP-101]
VKYLLDTNILIYLLKNRPESVAQRVNALPADASLNMSFFTYAELLKGAERSSRKAEVLRQLDRLTRQVPVIYDGTARLCE
HYAVHFTRLKQAGTPIGANDLWIACHALALDATLVTHNTREFERIDGLMLEDWAS

Download         Length: 408 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9682.70 Da        Isoelectric Point: 4.0048

>AT256993 WP_259757473.1 NZ_CP104011:940510-940770 [Pseudomonas sp. GCEP-101]
MPTSTLTTRVFMNGNSQAVRIPQEFRLDVGSVEITRKDNGDLVIHPIPQDRGAALMEALQGFDEDFLEALDDEQRDQPPA
QDRDEL

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References