256992

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 779504..780065 Replicon chromosome
Accession NZ_CP104009
Organism Mycoplasma feriruminatoris strain L15220

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MFERI15220_RS03395 Protein ID WP_278287774.1
Coordinates 779504..779800 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID L5LA09
Locus tag MFERI15220_RS03400 Protein ID WP_008362623.1
Coordinates 779793..780065 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MFERI15220_RS03375 (MFERI15220_00673) 774648..775277 + 630 WP_278287770.1 beta-phosphoglucomutase -
MFERI15220_RS03380 (MFERI15220_00674) 775384..777012 + 1629 WP_278287771.1 LppA family lipoprotein -
MFERI15220_RS03385 (MFERI15220_00675) 777044..777925 - 882 WP_278287772.1 Cof-type HAD-IIB family hydrolase -
MFERI15220_RS03390 (MFERI15220_00676) 778174..779469 + 1296 WP_278287773.1 ATP-binding protein -
MFERI15220_RS03395 (MFERI15220_00677) 779504..779800 - 297 WP_278287774.1 type II toxin-antitoxin system YafQ family toxin Toxin
MFERI15220_RS03400 (MFERI15220_00678) 779793..780065 - 273 WP_008362623.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MFERI15220_RS03405 (MFERI15220_00679) 780250..781419 - 1170 WP_278287775.1 site-specific DNA-methyltransferase -
MFERI15220_RS03410 (MFERI15220_00680) 781572..784697 - 3126 WP_278287776.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-87)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11452.38 Da        Isoelectric Point: 9.8106

>T256992 WP_278287774.1 NZ_CP104009:c779800-779504 [Mycoplasma feriruminatoris]
MTKYKIVTTKFKKDLKLAKKQNKDLNKLDYVINILTQGKELDAKYQDHSLTGIYKEYRECHIDPDLLIYKKDDDKIVIIM
LRLGSHSNLFEKQKNY

Download         Length: 297 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10257.67 Da        Isoelectric Point: 4.8483

>AT256992 WP_008362623.1 NZ_CP104009:c780065-779793 [Mycoplasma feriruminatoris]
MKTTNLNVRIDKEVKHDAEAIFNELGLSTSAAINMFFKATIRNNSLPFSTKLDTPNKETLLAMKEAEELLKDPNTKYYSS
FKELLETLDD

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB L5LA09

References