Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 821320..821881 Replicon chromosome
Accession NZ_CP104008
Organism Mycoplasma feriruminatoris strain L14822

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MFERI14822_RS03535 Protein ID WP_278307434.1
Coordinates 821320..821616 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MFERI14822_RS03540 Protein ID WP_278300265.1
Coordinates 821609..821881 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MFERI14822_RS03515 (MFERI14822_00702) 816459..817088 + 630 WP_278299862.1 beta-phosphoglucomutase -
MFERI14822_RS03520 (MFERI14822_00703) 817196..818827 + 1632 WP_278307433.1 LppA family lipoprotein -
MFERI14822_RS03525 (MFERI14822_00704) 818860..819741 - 882 WP_278287772.1 Cof-type HAD-IIB family hydrolase -
MFERI14822_RS03530 (MFERI14822_00705) 819990..821285 + 1296 WP_278300263.1 ATP-binding protein -
MFERI14822_RS03535 (MFERI14822_00706) 821320..821616 - 297 WP_278307434.1 type II toxin-antitoxin system YafQ family toxin Toxin
MFERI14822_RS03540 (MFERI14822_00707) 821609..821881 - 273 WP_278300265.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MFERI14822_RS03545 (MFERI14822_00708) 822065..823234 - 1170 WP_278307435.1 site-specific DNA-methyltransferase -
MFERI14822_RS03550 (MFERI14822_00709) 823400..826507 - 3108 WP_278307436.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-87)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11392.37 Da        Isoelectric Point: 9.9386

>T256991 WP_278307434.1 NZ_CP104008:c821616-821320 [Mycoplasma feriruminatoris]
MTKYKIVTTKFKKDLKLAKKQNKDLNKLDYVINILIQGKELDAKYQDHSLTGIYKGYRECHIDPDLLIYKKDDDKIVIIM
LRLGSHSNLFEKQKNY

Download         Length: 297 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10239.64 Da        Isoelectric Point: 4.8483

>AT256991 WP_278300265.1 NZ_CP104008:c821881-821609 [Mycoplasma feriruminatoris]
MKTTNLNVRIDKEVKHDAEAIFNELGLSTSAAINMFFKATIRNNSLPFSTKLDTPNKETLLAIKEAEELLKDPNTKYYSS
FKELLETLDD

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References