Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 3067814..3068814 | Replicon | chromosome |
| Accession | NZ_CP104006 | ||
| Organism | Yersinia alsatica strain SCPM-O-B-7604 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A0T9TCX5 |
| Locus tag | N0H69_RS13725 | Protein ID | WP_050134509.1 |
| Coordinates | 3067814..3068272 (-) | Length | 153 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A0T9TCZ6 |
| Locus tag | N0H69_RS13730 | Protein ID | WP_050151177.1 |
| Coordinates | 3068368..3068814 (-) | Length | 149 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N0H69_RS13695 (N0H69_13695) | 3063709..3064374 | + | 666 | WP_050107120.1 | phage shock protein PspA | - |
| N0H69_RS13700 (N0H69_13700) | 3064474..3064701 | + | 228 | WP_032910193.1 | envelope stress response membrane protein PspB | - |
| N0H69_RS13705 (N0H69_13705) | 3064701..3065060 | + | 360 | WP_050107119.1 | envelope stress response membrane protein PspC | - |
| N0H69_RS13710 (N0H69_13710) | 3065109..3065348 | + | 240 | WP_050151175.1 | phage shock protein PspD | - |
| N0H69_RS13715 (N0H69_13715) | 3065329..3066726 | + | 1398 | WP_050121288.1 | YcjX family protein | - |
| N0H69_RS13720 (N0H69_13720) | 3066723..3067787 | + | 1065 | WP_050151176.1 | YcjF family protein | - |
| N0H69_RS13725 (N0H69_13725) | 3067814..3068272 | - | 459 | WP_050134509.1 | RES family NAD+ phosphorylase | Toxin |
| N0H69_RS13730 (N0H69_13730) | 3068368..3068814 | - | 447 | WP_050151177.1 | type II toxin-antitoxin system antitoxin Xre | Antitoxin |
| N0H69_RS13735 (N0H69_13735) | 3069133..3070710 | + | 1578 | WP_050151258.1 | transcriptional regulator TyrR | - |
| N0H69_RS13740 (N0H69_13740) | 3070858..3071361 | - | 504 | WP_050134508.1 | thiol peroxidase | - |
| N0H69_RS13745 (N0H69_13745) | 3071514..3072485 | + | 972 | WP_050151178.1 | L-Ala-D/L-Glu epimerase | - |
| N0H69_RS13750 (N0H69_13750) | 3072482..3073189 | - | 708 | WP_050151179.1 | murein tripeptide amidase MpaA | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 153 a.a. Molecular weight: 17206.50 Da Isoelectric Point: 4.5564
>T256989 WP_050134509.1 NZ_CP104006:c3068272-3067814 [Yersinia alsatica]
MIFYRIVMRHYLASTWTGYGAEIYGGRWNHKGHAAIYLASSVSLAMLETLVHIQDSSTLSEFELFQIEIDDSNIMLLQPQ
DWPTDWRSDPAPVATMDIGTEWLESESSLGLLVPSTLVPSENNLLVNPRHQDFQACLTSVKPLSFSFDSRLK
MIFYRIVMRHYLASTWTGYGAEIYGGRWNHKGHAAIYLASSVSLAMLETLVHIQDSSTLSEFELFQIEIDDSNIMLLQPQ
DWPTDWRSDPAPVATMDIGTEWLESESSLGLLVPSTLVPSENNLLVNPRHQDFQACLTSVKPLSFSFDSRLK
Download Length: 459 bp
Antitoxin
Download Length: 149 a.a. Molecular weight: 16337.74 Da Isoelectric Point: 8.0956
>AT256989 WP_050151177.1 NZ_CP104006:c3068814-3068368 [Yersinia alsatica]
MRAYHPAPATKTDALWREIGLPASRGPVLVDSIKMGFSVDVIDSIHLWASIPKAEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDKNRAITWMSTPIKGLGQRSPDSLLETETGALEVCDLIGRLEHGVFS
MRAYHPAPATKTDALWREIGLPASRGPVLVDSIKMGFSVDVIDSIHLWASIPKAEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDKNRAITWMSTPIKGLGQRSPDSLLETETGALEVCDLIGRLEHGVFS
Download Length: 447 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0T9TCX5 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0T9TCZ6 |