Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3939980..3940637 Replicon chromosome
Accession NZ_CP104001
Organism Enterobacter roggenkampii strain RX.G5M56

Toxin (Protein)


Gene name cptA Uniprot ID A0A1H8U0Q4
Locus tag N0B38_RS18680 Protein ID WP_021242050.1
Coordinates 3939980..3940390 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID W7NX65
Locus tag N0B38_RS18685 Protein ID WP_006178375.1
Coordinates 3940371..3940637 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0B38_RS18660 (N0B38_18660) 3935973..3937706 - 1734 WP_135345484.1 single-stranded-DNA-specific exonuclease RecJ -
N0B38_RS18665 (N0B38_18665) 3937712..3938425 - 714 WP_008499708.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
N0B38_RS18670 (N0B38_18670) 3938454..3939350 - 897 WP_008499709.1 site-specific tyrosine recombinase XerD -
N0B38_RS18675 (N0B38_18675) 3939452..3939973 + 522 WP_008499710.1 flavodoxin FldB -
N0B38_RS18680 (N0B38_18680) 3939980..3940390 - 411 WP_021242050.1 protein YgfX Toxin
N0B38_RS18685 (N0B38_18685) 3940371..3940637 - 267 WP_006178375.1 FAD assembly factor SdhE Antitoxin
N0B38_RS18690 (N0B38_18690) 3940932..3941912 + 981 WP_008499712.1 tRNA-modifying protein YgfZ -
N0B38_RS18695 (N0B38_18695) 3941997..3942656 - 660 WP_021242052.1 hemolysin III family protein -
N0B38_RS18700 (N0B38_18700) 3942922..3943653 + 732 WP_021242053.1 MurR/RpiR family transcriptional regulator -
N0B38_RS18705 (N0B38_18705) 3943770..3945203 + 1434 WP_023294510.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16097.08 Da        Isoelectric Point: 10.9468

>T256978 WP_021242050.1 NZ_CP104001:c3940390-3939980 [Enterobacter roggenkampii]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNCGMMLRLRKVDGGRCQHLWLAADSMDAAEWRDLRRMLLQQTTQG

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10569.05 Da        Isoelectric Point: 5.1340

>AT256978 WP_006178375.1 NZ_CP104001:c3940637-3940371 [Enterobacter roggenkampii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H8U0Q4

Antitoxin

Source ID Structure
AlphaFold DB W7NX65

References