256969

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 16221..16740 Replicon plasmid p3
Accession NZ_CP104000
Organism Ketogulonicigenium vulgare strain D3_3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NZF41_RS16475 Protein ID WP_273692383.1
Coordinates 16221..16505 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NZF41_RS16480 Protein ID WP_273692385.1
Coordinates 16495..16740 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NZF41_RS16455 11667..13211 - 1545 WP_273692379.1 class I SAM-dependent DNA methyltransferase -
NZF41_RS16460 13798..14637 + 840 WP_273692380.1 PRC-barrel domain-containing protein -
NZF41_RS16465 14667..15044 + 378 WP_273692381.1 PRC-barrel domain-containing protein -
NZF41_RS16470 15094..15543 - 450 WP_273692382.1 TspO/MBR family protein -
NZF41_RS16475 16221..16505 - 285 WP_273692383.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NZF41_RS16480 16495..16740 - 246 WP_273692385.1 antitoxin Antitoxin
NZF41_RS16485 17423..17773 + 351 WP_273692386.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
NZF41_RS16490 17787..18137 + 351 WP_273692348.1 DUF983 domain-containing protein -
NZF41_RS16495 18476..19135 + 660 WP_273692350.1 HAD family phosphatase -
NZF41_RS16500 19371..19796 + 426 WP_273692352.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..35511 35511
- flank IS/Tn - - 20265..20612 347


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10847.74 Da        Isoelectric Point: 10.7301

>T256969 WP_273692383.1 NZ_CP104000:c16505-16221 [Ketogulonicigenium vulgare]
MSYKLEFLPSALKEWRKLDSVIADQFRRKLLKLRDNPRVSSLALRNLKDCYKVKLASAGFRLVYQVVDDRMIVQVVAVGK
RSNGDVYDTASKRV

Download         Length: 285 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8812.00 Da        Isoelectric Point: 4.5026

>AT256969 WP_273692385.1 NZ_CP104000:c16740-16495 [Ketogulonicigenium vulgare]
MQRVSAGLAMSISDLKKNPSAAFDVSGGQPVAILNHNKVVGYMVTPDRYEALLEALDDARLAETIRERSGEVPVALDWNE
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References