256962

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 2057216..2057703 Replicon chromosome
Accession NZ_CP103983
Organism Cysteiniphilum sp. QT6929

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag NYP54_RS08960 Protein ID WP_283156214.1
Coordinates 2057434..2057703 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag NYP54_RS08955 Protein ID WP_283156213.1
Coordinates 2057216..2057434 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP54_RS08935 (NYP54_08935) 2053028..2053537 + 510 WP_283156209.1 hypothetical protein -
NYP54_RS08940 (NYP54_08940) 2053717..2054178 - 462 WP_283156210.1 hypothetical protein -
NYP54_RS08945 (NYP54_08945) 2054371..2055453 - 1083 WP_283156211.1 LysM domain-containing protein -
NYP54_RS08950 (NYP54_08950) 2055517..2057070 - 1554 WP_283156212.1 murein biosynthesis integral membrane protein MurJ -
NYP54_RS08955 (NYP54_08955) 2057216..2057434 + 219 WP_283156213.1 DUF6290 family protein Antitoxin
NYP54_RS08960 (NYP54_08960) 2057434..2057703 + 270 WP_283156214.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NYP54_RS08965 (NYP54_08965) 2057797..2059200 - 1404 WP_283156215.1 asparagine--tRNA ligase -
NYP54_RS08970 (NYP54_08970) 2059674..2060561 + 888 WP_151192831.1 glycine--tRNA ligase subunit alpha -
NYP54_RS08975 (NYP54_08975) 2060558..2060743 - 186 WP_283156216.1 hypothetical protein -
NYP54_RS08980 (NYP54_08980) 2060835..2062286 + 1452 WP_283156217.1 potassium transporter TrkG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin

Protein of unknown function DUF6290

(3-68)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10497.23 Da        Isoelectric Point: 10.6462

>T256962 WP_283156214.1 NZ_CP103983:2057434-2057703 [Cysteiniphilum sp. QT6929]
MWRVVFDKKAEKQFNGLDSQVKKRIAKFIDERLIPSSDPRDLGKPLVGKSFGNHIRFRIGDYRLICDIQDQEITVLVLRI
GHRREIYRG

Download         Length: 270 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8152.23 Da        Isoelectric Point: 5.0958

>AT256962 WP_283156213.1 NZ_CP103983:2057216-2057434 [Cysteiniphilum sp. QT6929]
MANVRFNAEIQDRLAYLAKETGRTISYYIREAVESKIEDLEDIYLAEKALEDLKAGRSSVVSWGSIKKGNNL

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References