256960

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1525660..1526315 Replicon chromosome
Accession NZ_CP103983
Organism Cysteiniphilum sp. QT6929

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NYP54_RS06610 Protein ID WP_283155847.1
Coordinates 1525896..1526315 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NYP54_RS06605 Protein ID WP_283155846.1
Coordinates 1525660..1525899 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP54_RS06580 (NYP54_06580) 1520858..1522876 - 2019 WP_283155841.1 M3 family metallopeptidase -
NYP54_RS06585 (NYP54_06585) 1522971..1523615 + 645 WP_283155842.1 site-2 protease family protein -
NYP54_RS06590 (NYP54_06590) 1523631..1524002 + 372 WP_283155843.1 MTH938/NDUFAF3 family protein -
NYP54_RS06595 (NYP54_06595) 1524149..1524622 + 474 WP_283155844.1 TUL4 family lipoprotein -
NYP54_RS06600 (NYP54_06600) 1524821..1525471 - 651 WP_283155845.1 4'-phosphopantetheinyl transferase superfamily protein -
NYP54_RS06605 (NYP54_06605) 1525660..1525899 + 240 WP_283155846.1 antitoxin Antitoxin
NYP54_RS06610 (NYP54_06610) 1525896..1526315 + 420 WP_283155847.1 type II toxin-antitoxin system VapC family toxin Toxin
NYP54_RS06615 (NYP54_06615) 1526393..1526644 + 252 WP_117001514.1 hypothetical protein -
NYP54_RS06620 (NYP54_06620) 1526681..1528423 + 1743 WP_283155848.1 proline--tRNA ligase -
NYP54_RS06625 (NYP54_06625) 1528493..1529467 + 975 WP_283155849.1 KpsF/GutQ family sugar-phosphate isomerase -
NYP54_RS06630 (NYP54_06630) 1529566..1529823 - 258 WP_117001517.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15229.74 Da        Isoelectric Point: 5.1594

>T256960 WP_283155847.1 NZ_CP103983:1525896-1526315 [Cysteiniphilum sp. QT6929]
MILVDTNVISEPLKPRPNVSVIKWLDDQLIDALYLSTISIAEIRFGIAALPSGKKKTTLEESLESTILPLFTNRVLSFDQ
NAAKIYALSMAKARKCGITVGIADAYIAAIAKANSMTIATRDTNPFDALEVPYINPWEC

Download         Length: 420 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8805.21 Da        Isoelectric Point: 10.5624

>AT256960 WP_283155846.1 NZ_CP103983:1525660-1525899 [Cysteiniphilum sp. QT6929]
MAVLTIRNVPDDVHRALKAKALKHGRSTEAEIREILKNAVEHQSQVKLGSLLSSIRKEVGVIKLDTHRDKTPPSPLDFT

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References