Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 478446..479353 Replicon chromosome
Accession NZ_CP103983
Organism Cysteiniphilum sp. QT6929

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag NYP54_RS02080 Protein ID WP_283156952.1
Coordinates 478446..478916 (-) Length 157 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag NYP54_RS02085 Protein ID WP_283156953.1
Coordinates 478913..479353 (-) Length 147 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP54_RS02055 (NYP54_02055) 473468..474190 - 723 WP_283156947.1 TonB family protein -
NYP54_RS02060 (NYP54_02060) 474201..476276 - 2076 WP_283156948.1 TonB-dependent receptor -
NYP54_RS02065 (NYP54_02065) 476306..476719 - 414 WP_283156949.1 biopolymer transporter ExbD -
NYP54_RS02070 (NYP54_02070) 476716..477477 - 762 WP_283156950.1 MotA/TolQ/ExbB proton channel family protein -
NYP54_RS02075 (NYP54_02075) 477483..478247 - 765 WP_283156951.1 DUF2470 domain-containing protein -
NYP54_RS02080 (NYP54_02080) 478446..478916 - 471 WP_283156952.1 RES family NAD+ phosphorylase Toxin
NYP54_RS02085 (NYP54_02085) 478913..479353 - 441 WP_283156953.1 DUF2384 domain-containing protein Antitoxin
NYP54_RS02090 (NYP54_02090) 479430..480209 - 780 WP_283156954.1 acetolactate decarboxylase -
NYP54_RS02095 (NYP54_02095) 480418..481269 - 852 WP_283157504.1 isoaspartyl peptidase/L-asparaginase -
NYP54_RS02100 (NYP54_02100) 481317..482138 - 822 WP_151193467.1 cyanophycinase -
NYP54_RS02105 (NYP54_02105) 482158..483858 - 1701 WP_283156955.1 Mur ligase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(7-150)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(28-87)


Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 17693.48 Da        Isoelectric Point: 8.2398

>T256958 WP_283156952.1 NZ_CP103983:c478916-478446 [Cysteiniphilum sp. QT6929]
MSKVFAYRLVKSKFAQDAFTGDGARIYGGRWNNKGSPCVYCAGSESLAILEIFVHLEDYAILPNYTLFQIELPKSEINYL
KPELLPHSWQDQPAPPETADIGDQWLKRCESLILAVPSVIVPREYNYILNPLHKGFAKVVKKAKVLDFSFDTRLAK

Download         Length: 471 bp

Antitoxin


Download         Length: 147 a.a.        Molecular weight: 16404.55 Da        Isoelectric Point: 8.0586

>AT256958 WP_283156953.1 NZ_CP103983:c479353-478913 [Cysteiniphilum sp. QT6929]
MQQGNQSNQSNQNNFWDAVGIPSRGERLYQAIHEGFSCEVFSKLADISGIEKNQLAKITTIAPASLNRRYKAGFFTEAES
DRLYRYAEVYKSALNLFEGHDQKALHWLMSPVNGLGGRKPIEMLRTSAETKAVLDLIGRLEHGVFV

Download         Length: 441 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References