Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 478446..479353 | Replicon | chromosome |
| Accession | NZ_CP103983 | ||
| Organism | Cysteiniphilum sp. QT6929 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | NYP54_RS02080 | Protein ID | WP_283156952.1 |
| Coordinates | 478446..478916 (-) | Length | 157 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | NYP54_RS02085 | Protein ID | WP_283156953.1 |
| Coordinates | 478913..479353 (-) | Length | 147 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NYP54_RS02055 (NYP54_02055) | 473468..474190 | - | 723 | WP_283156947.1 | TonB family protein | - |
| NYP54_RS02060 (NYP54_02060) | 474201..476276 | - | 2076 | WP_283156948.1 | TonB-dependent receptor | - |
| NYP54_RS02065 (NYP54_02065) | 476306..476719 | - | 414 | WP_283156949.1 | biopolymer transporter ExbD | - |
| NYP54_RS02070 (NYP54_02070) | 476716..477477 | - | 762 | WP_283156950.1 | MotA/TolQ/ExbB proton channel family protein | - |
| NYP54_RS02075 (NYP54_02075) | 477483..478247 | - | 765 | WP_283156951.1 | DUF2470 domain-containing protein | - |
| NYP54_RS02080 (NYP54_02080) | 478446..478916 | - | 471 | WP_283156952.1 | RES family NAD+ phosphorylase | Toxin |
| NYP54_RS02085 (NYP54_02085) | 478913..479353 | - | 441 | WP_283156953.1 | DUF2384 domain-containing protein | Antitoxin |
| NYP54_RS02090 (NYP54_02090) | 479430..480209 | - | 780 | WP_283156954.1 | acetolactate decarboxylase | - |
| NYP54_RS02095 (NYP54_02095) | 480418..481269 | - | 852 | WP_283157504.1 | isoaspartyl peptidase/L-asparaginase | - |
| NYP54_RS02100 (NYP54_02100) | 481317..482138 | - | 822 | WP_151193467.1 | cyanophycinase | - |
| NYP54_RS02105 (NYP54_02105) | 482158..483858 | - | 1701 | WP_283156955.1 | Mur ligase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 157 a.a. Molecular weight: 17693.48 Da Isoelectric Point: 8.2398
>T256958 WP_283156952.1 NZ_CP103983:c478916-478446 [Cysteiniphilum sp. QT6929]
MSKVFAYRLVKSKFAQDAFTGDGARIYGGRWNNKGSPCVYCAGSESLAILEIFVHLEDYAILPNYTLFQIELPKSEINYL
KPELLPHSWQDQPAPPETADIGDQWLKRCESLILAVPSVIVPREYNYILNPLHKGFAKVVKKAKVLDFSFDTRLAK
MSKVFAYRLVKSKFAQDAFTGDGARIYGGRWNNKGSPCVYCAGSESLAILEIFVHLEDYAILPNYTLFQIELPKSEINYL
KPELLPHSWQDQPAPPETADIGDQWLKRCESLILAVPSVIVPREYNYILNPLHKGFAKVVKKAKVLDFSFDTRLAK
Download Length: 471 bp
Antitoxin
Download Length: 147 a.a. Molecular weight: 16404.55 Da Isoelectric Point: 8.0586
>AT256958 WP_283156953.1 NZ_CP103983:c479353-478913 [Cysteiniphilum sp. QT6929]
MQQGNQSNQSNQNNFWDAVGIPSRGERLYQAIHEGFSCEVFSKLADISGIEKNQLAKITTIAPASLNRRYKAGFFTEAES
DRLYRYAEVYKSALNLFEGHDQKALHWLMSPVNGLGGRKPIEMLRTSAETKAVLDLIGRLEHGVFV
MQQGNQSNQSNQNNFWDAVGIPSRGERLYQAIHEGFSCEVFSKLADISGIEKNQLAKITTIAPASLNRRYKAGFFTEAES
DRLYRYAEVYKSALNLFEGHDQKALHWLMSPVNGLGGRKPIEMLRTSAETKAVLDLIGRLEHGVFV
Download Length: 441 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|