256916

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 5887301..5889030 Replicon chromosome
Accession NZ_CP103965
Organism Pseudomonas sp. N3-W

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag NYP20_RS25930 Protein ID WP_259496901.1
Coordinates 5887301..5887945 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag NYP20_RS25935 Protein ID WP_259496902.1
Coordinates 5887942..5889030 (+) Length 363 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP20_RS25905 (NYP20_25905) 5883012..5883539 + 528 WP_162439598.1 inorganic diphosphatase -
NYP20_RS25910 (NYP20_25910) 5883774..5884520 + 747 WP_259496897.1 helix-turn-helix transcriptional regulator -
NYP20_RS25915 (NYP20_25915) 5885061..5885282 + 222 WP_259496898.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
NYP20_RS25920 (NYP20_25920) 5885636..5886556 + 921 WP_259496899.1 restriction endonuclease -
NYP20_RS25925 (NYP20_25925) 5886723..5887304 + 582 WP_259496900.1 DUF4433 domain-containing protein -
NYP20_RS25930 (NYP20_25930) 5887301..5887945 + 645 WP_259496901.1 DUF4433 domain-containing protein Toxin
NYP20_RS25935 (NYP20_25935) 5887942..5889030 + 1089 WP_259496902.1 macro domain-containing protein Antitoxin
NYP20_RS25940 (NYP20_25940) 5889078..5889893 - 816 WP_259496903.1 DUF2135 domain-containing protein -
NYP20_RS25945 (NYP20_25945) 5889897..5891516 - 1620 WP_259496905.1 DUF2300 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24692.10 Da        Isoelectric Point: 6.4904

>T256916 WP_259496901.1 NZ_CP103965:5887301-5887945 [Pseudomonas sp. N3-W]
MNYTSLNPEKALIWRIIHRDNLLWILDNGLHCASSDVQAPQYVNIGNADLIDKRRNRCVPIAPAGVLADYVPFYFTPFSV
MMKNIHSGWSVQQRSNDEIVILVSSLYRVEQLGLPFVFTNAHAYPDWTDYYSDLANLGEVDWSILQRRDFKRDSDDPRKM
ERYQAEALIHHHLPITGLLGIMCYNDAVKERIEQDVAARGLALSVHARPGWYFQ

Download         Length: 645 bp

Antitoxin


Download         Length: 363 a.a.        Molecular weight: 40570.56 Da        Isoelectric Point: 7.0980

>AT256916 WP_259496902.1 NZ_CP103965:5887942-5889030 [Pseudomonas sp. N3-W]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAENYRIYSAACKAGEVETGKVHVTAANELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLIENNVKSVAVPPLGAGNGGLKWPEVREQIVNVLSDLDVDVLVFEPSNQYLNVAKRSG
VEQLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKLPNATNPLDLKFVAHKYGPYANRLEHLLNNLDGSYLH
CDKRISDAGISDVIWFDQERKAFLQTYLKTEAKEYSQALERTAKLIDGFESPFGMELLATVDWLLSQEGISPTVPAVREA
LKHWDGGAGAAARKSRLFDDSALDIALKRLTSSSFRPEVAAC

Download         Length: 1089 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References