Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 1802225..1803264 | Replicon | chromosome |
| Accession | NZ_CP103965 | ||
| Organism | Pseudomonas sp. N3-W | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | NYP20_RS08260 | Protein ID | WP_259500818.1 |
| Coordinates | 1802225..1802800 (-) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | NYP20_RS08265 | Protein ID | WP_259503120.1 |
| Coordinates | 1802797..1803264 (-) | Length | 156 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NYP20_RS08235 (NYP20_08235) | 1798859..1799395 | + | 537 | WP_259500807.1 | DsbE family thiol:disulfide interchange protein | - |
| NYP20_RS08240 (NYP20_08240) | 1799392..1799862 | + | 471 | WP_259500809.1 | cytochrome c-type biogenesis protein CcmH | - |
| NYP20_RS08245 (NYP20_08245) | 1799859..1801061 | + | 1203 | WP_259500811.1 | c-type cytochrome biogenesis protein CcmI | - |
| NYP20_RS08250 (NYP20_08250) | 1801076..1801483 | + | 408 | WP_259500813.1 | hypothetical protein | - |
| NYP20_RS08255 (NYP20_08255) | 1801642..1802217 | + | 576 | WP_259500815.1 | phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN | - |
| NYP20_RS08260 (NYP20_08260) | 1802225..1802800 | - | 576 | WP_259500818.1 | PIN domain-containing protein | Toxin |
| NYP20_RS08265 (NYP20_08265) | 1802797..1803264 | - | 468 | WP_259503120.1 | helix-turn-helix domain-containing protein | Antitoxin |
| NYP20_RS08270 (NYP20_08270) | 1803553..1803765 | + | 213 | WP_259500819.1 | type II toxin-antitoxin system HicA family toxin | - |
| NYP20_RS08275 (NYP20_08275) | 1803765..1804169 | + | 405 | WP_259500821.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| NYP20_RS08280 (NYP20_08280) | 1804244..1805452 | - | 1209 | WP_259500823.1 | MFS transporter | - |
| NYP20_RS08285 (NYP20_08285) | 1805690..1806307 | + | 618 | WP_259500825.1 | DUF5666 domain-containing protein | - |
| NYP20_RS08290 (NYP20_08290) | 1806543..1807541 | - | 999 | WP_259500827.1 | sulfate ABC transporter substrate-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21650.06 Da Isoelectric Point: 5.6385
>T256913 WP_259500818.1 NZ_CP103965:c1802800-1802225 [Pseudomonas sp. N3-W]
VRHSPFTAVYDACVLYPAPLRDFLMWLALSGRFRAKWSEEIHNEWKRNLLKNRPDLMPEQLDRTSGLMEQAIPDACVYGY
EALIDGLVLPDVDDRHVLAVAIRCNASVIVTFNQKDFPCAVLRPYGIEAQHPDEFVDNLMDLDPAAVIAAAQRQRQQLKM
PPMDVSAYLNLLLRQGLVQSSKALTLYQAIL
VRHSPFTAVYDACVLYPAPLRDFLMWLALSGRFRAKWSEEIHNEWKRNLLKNRPDLMPEQLDRTSGLMEQAIPDACVYGY
EALIDGLVLPDVDDRHVLAVAIRCNASVIVTFNQKDFPCAVLRPYGIEAQHPDEFVDNLMDLDPAAVIAAAQRQRQQLKM
PPMDVSAYLNLLLRQGLVQSSKALTLYQAIL
Download Length: 576 bp
Antitoxin
Download Length: 156 a.a. Molecular weight: 17346.83 Da Isoelectric Point: 6.7630
>AT256913 WP_259503120.1 NZ_CP103965:c1803264-1802797 [Pseudomonas sp. N3-W]
MSPVIHSPLTLPIEREVQAAIEGQRTLAAWLATRFETQQIQIFDEQNKAHSVELPTSALRLLVDILAELAAGNAVKVVPV
HAELTTQEAADLLNVSRPHLIKLLESGDLSYHKTGKHRRVRFADLMDYKNRRDTASERAMTLLAEQAQALRTGYE
MSPVIHSPLTLPIEREVQAAIEGQRTLAAWLATRFETQQIQIFDEQNKAHSVELPTSALRLLVDILAELAAGNAVKVVPV
HAELTTQEAADLLNVSRPHLIKLLESGDLSYHKTGKHRRVRFADLMDYKNRRDTASERAMTLLAEQAQALRTGYE
Download Length: 468 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|