Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 352941..353578 Replicon chromosome
Accession NZ_CP103965
Organism Pseudomonas sp. N3-W

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NYP20_RS01610 Protein ID WP_259498367.1
Coordinates 352941..353348 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NYP20_RS01615 Protein ID WP_259498368.1
Coordinates 353348..353578 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP20_RS01590 (NYP20_01590) 348615..349310 - 696 WP_259498360.1 ABC transporter permease -
NYP20_RS01595 (NYP20_01595) 349389..350138 - 750 WP_259498362.1 ABC transporter substrate-binding protein -
NYP20_RS01600 (NYP20_01600) 350152..350925 - 774 WP_259498364.1 ABC transporter ATP-binding protein -
NYP20_RS01605 (NYP20_01605) 351476..352867 + 1392 WP_259498366.1 GABA permease -
NYP20_RS01610 (NYP20_01610) 352941..353348 - 408 WP_259498367.1 tRNA(fMet)-specific endonuclease VapC Toxin
NYP20_RS01615 (NYP20_01615) 353348..353578 - 231 WP_259498368.1 antitoxin Antitoxin
NYP20_RS01620 (NYP20_01620) 353749..354213 - 465 WP_259498370.1 hypothetical protein -
NYP20_RS01625 (NYP20_01625) 354220..354633 - 414 WP_259498372.1 hypothetical protein -
NYP20_RS01630 (NYP20_01630) 354671..355639 - 969 WP_259498374.1 alpha/beta fold hydrolase -
NYP20_RS01635 (NYP20_01635) 355980..356429 + 450 WP_259498376.1 carboxypeptidase regulatory-like domain-containing protein -
NYP20_RS01645 (NYP20_01645) 356840..357112 - 273 WP_010464608.1 oxidative damage protection protein -
NYP20_RS01650 (NYP20_01650) 357109..358176 - 1068 WP_259498382.1 A/G-specific adenine glycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15130.45 Da        Isoelectric Point: 6.8631

>T256912 WP_259498367.1 NZ_CP103965:c353348-352941 [Pseudomonas sp. N3-W]
MIKFMLDTNICIFTIKNKPQVVREAFNRHHSQLCISTITLMELIYGAEKSAAPEKNLSIVESFAARLEILPFDSDAAAHT
GMIRSELAKAGTPIGPYDQMIAGHARSRGFTVVTNNLREFERVPGLRVEDWVQPE

Download         Length: 408 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8501.59 Da        Isoelectric Point: 4.5045

>AT256912 WP_259498368.1 NZ_CP103965:c353578-353348 [Pseudomonas sp. N3-W]
MEQTTLFMSNRSQAVRLPKAVAMPGDVKRVEVIAIGRARLITPAGEAWDSWFDGESVSADFMADREQPTDQVRESF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References