256907

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1006027..1006800 Replicon chromosome
Accession NZ_CP103964
Organism Staphylococcus hyicus strain MM2101

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag NZD48_RS04880 Protein ID WP_167693803.1
Coordinates 1006645..1006800 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID A0A0A8HNH4
Locus tag NZD48_RS04875 Protein ID WP_039644857.1
Coordinates 1006027..1006626 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NZD48_RS04855 (NZD48_04855) 1002337..1003059 + 723 WP_039644852.1 amino acid ABC transporter ATP-binding protein -
NZD48_RS04860 (NZD48_04860) 1003224..1004351 + 1128 WP_252547564.1 tRNA epoxyqueuosine(34) reductase QueG -
NZD48_RS04865 (NZD48_04865) 1004354..1004824 + 471 WP_039644854.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
NZD48_RS04870 (NZD48_04870) 1004840..1006009 + 1170 WP_259490305.1 N-acetylglucosamine-6-phosphate deacetylase -
NZD48_RS04875 (NZD48_04875) 1006027..1006626 + 600 WP_039644857.1 glucosamine-6-phosphate isomerase Antitoxin
NZD48_RS04880 (NZD48_04880) 1006645..1006800 + 156 WP_167693803.1 SAS053 family protein Toxin
NZD48_RS04885 (NZD48_04885) 1006956..1007360 + 405 WP_039644859.1 hypothetical protein -
NZD48_RS04890 (NZD48_04890) 1007518..1008903 + 1386 WP_259490309.1 class II fumarate hydratase -
NZD48_RS04895 (NZD48_04895) 1008925..1010451 + 1527 WP_259490310.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5989.31 Da        Isoelectric Point: 3.9940

>T256907 WP_167693803.1 NZ_CP103964:1006645-1006800 [Staphylococcus hyicus]
MSEEKHIEHENEMVDNFDDLVQLGKEMEQISETNDQDKLNQSHDSEGRSNQ

Download         Length: 156 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22363.41 Da        Isoelectric Point: 6.0248

>AT256907 WP_039644857.1 NZ_CP103964:1006027-1006626 [Staphylococcus hyicus]
MAMNFKVFKDKDTAAIYAADIIRKQFNNNPTTIAGFHLNEEAAPVLDYLKRNVDDHAVDFSQIHILDYDKQTSYFKALGV
PEKQIHEIPEEDEVEKFIERKAKTKDNKGKLTLQVVSINNKGEFGIPVTNGLKPAREIFVVVTGSEKADVIKKLYEDNGN
TSFIPSSLKAHRMVNVILDEAAAQGLPDDVRAYFTSLYA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0A8HNH4

References