256905

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 853315..853848 Replicon chromosome
Accession NZ_CP103964
Organism Staphylococcus hyicus strain MM2101

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag NZD48_RS04005 Protein ID WP_259490155.1
Coordinates 853615..853848 (+) Length 78 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID A0A0A8HRR0
Locus tag NZD48_RS04000 Protein ID WP_039644657.1
Coordinates 853315..853602 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NZD48_RS03975 (NZD48_03975) 848608..849405 + 798 WP_259490151.1 hydroxyethylthiazole kinase -
NZD48_RS03980 (NZD48_03980) 849402..850040 + 639 WP_039644650.1 thiamine phosphate synthase -
NZD48_RS03985 (NZD48_03985) 850129..850995 + 867 WP_252538092.1 membrane protein insertase YidC -
NZD48_RS03990 (NZD48_03990) 851043..851675 - 633 WP_119635710.1 HD domain-containing protein -
NZD48_RS03995 (NZD48_03995) 851687..853177 - 1491 WP_259490153.1 cardiolipin synthase -
NZD48_RS04000 (NZD48_04000) 853315..853602 + 288 WP_039644657.1 copper-sensing transcriptional repressor CsoR Antitoxin
NZD48_RS04005 (NZD48_04005) 853615..853848 + 234 WP_259490155.1 heavy-metal-associated domain-containing protein Toxin
NZD48_RS04010 (NZD48_04010) 853841..854044 + 204 WP_039644660.1 cation transporter -
NZD48_RS04015 (NZD48_04015) 854174..856354 + 2181 WP_259490157.1 heavy metal translocating P-type ATPase -
NZD48_RS04020 (NZD48_04020) 856439..856579 + 141 WP_086375151.1 Lmo0850 family protein -
NZD48_RS04025 (NZD48_04025) 856737..857936 - 1200 WP_259490159.1 FtsW/RodA/SpoVE family cell cycle protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Metal-sensitive transcriptional repressor

(12-90)


Sequences

Toxin        


Download         Length: 78 a.a.        Molecular weight: 8923.16 Da        Isoelectric Point: 4.6104

>T256905 WP_259490155.1 NZ_CP103964:853615-853848 [Staphylococcus hyicus]
MQIDRVFVEGLDEEQQRTDLTQRLNHMIGVKEVSIDGHLQCVTLKYETPMNLNTLEKEIYDAGFKVLRTVKGEITNE

Download         Length: 234 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10999.56 Da        Isoelectric Point: 6.3268

>AT256905 WP_039644657.1 NZ_CP103964:853315-853602 [Staphylococcus hyicus]
MNDHAHHSEEIKKNLTSRLNRIEGQVRAINRMIDEDVYCDDVLTQIRATRSALNSVATKLLDYHMKGCITKKIEDGHETE
AMEELLVTFQKLMKD

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0A8HRR0

References