Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1(toxin)
Location 102578..103155 Replicon chromosome
Accession NZ_CP103872
Organism Herbaspirillum huttiense strain ZXN111

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NY669_RS00360 Protein ID WP_259433826.1
Coordinates 102578..102943 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NY669_RS00365 Protein ID WP_259433827.1
Coordinates 102937..103155 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NY669_RS00330 (NY669_00330) 97968..98153 + 186 WP_259433822.1 hypothetical protein -
NY669_RS00335 (NY669_00335) 98202..98447 + 246 WP_034332290.1 ferrous iron transport protein A -
NY669_RS00340 (NY669_00340) 98444..100270 + 1827 WP_259433823.1 ferrous iron transporter B -
NY669_RS00345 (NY669_00345) 100267..100554 + 288 WP_259433824.1 hypothetical protein -
NY669_RS00350 (NY669_00350) 100588..101793 - 1206 WP_034332296.1 threonine ammonia-lyase -
NY669_RS00355 (NY669_00355) 102154..102510 + 357 WP_259433825.1 hypothetical protein -
NY669_RS00360 (NY669_00360) 102578..102943 - 366 WP_259433826.1 type II toxin-antitoxin system VapC family toxin Toxin
NY669_RS00365 (NY669_00365) 102937..103155 - 219 WP_259433827.1 ribbon-helix-helix domain-containing protein Antitoxin
NY669_RS00370 (NY669_00370) 103298..103870 + 573 WP_259433828.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
NY669_RS00375 (NY669_00375) 103925..104791 - 867 WP_259433829.1 ABC transporter permease -
NY669_RS00380 (NY669_00380) 104807..105679 - 873 WP_259433830.1 ABC transporter ATP-binding protein -
NY669_RS00385 (NY669_00385) 105660..106601 - 942 WP_259435340.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-106)

Antitoxin

Ribbon-helix-helix protein, CopG

(4-41)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13987.18 Da        Isoelectric Point: 5.8943

>T256875 WP_259433826.1 NZ_CP103872:c102943-102578 [Herbaspirillum huttiense]
MVKALFDTNILVDYLNGIGHAKKELARYEYRAISIITWMEIMVGANEENEEALRYWLSSFQVISLDGFIAERAVQIRQQR
RIRLPDAIVWASAMEQSLLLISRNTKDFPADEPGVRVPYKI

Download         Length: 366 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8460.75 Da        Isoelectric Point: 8.5903

>AT256875 WP_259433827.1 NZ_CP103872:c103155-102937 [Herbaspirillum huttiense]
MSRILVDLPESQLADLTQLVESQRRPRAVIIREAIAAYITQHKLEHDTDVFGLWKKKKVDGLAYQRELRSEW

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References