Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 763897..764411 Replicon chromosome
Accession NZ_CP103871
Organism Actinacidiphila bryophytorum strain DS3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NYE86_RS03355 Protein ID WP_259437419.1
Coordinates 764151..764411 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NYE86_RS03350 Protein ID WP_259442673.1
Coordinates 763897..764154 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYE86_RS03335 (NYE86_03335) 760863..762098 - 1236 WP_259442672.1 APC family permease -
NYE86_RS03340 (NYE86_03340) 762198..763295 - 1098 WP_259437417.1 DUF3103 domain-containing protein -
NYE86_RS03345 (NYE86_03345) 763500..763814 - 315 WP_259437418.1 helix-turn-helix transcriptional regulator -
NYE86_RS03350 (NYE86_03350) 763897..764154 + 258 WP_259442673.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NYE86_RS03355 (NYE86_03355) 764151..764411 + 261 WP_259437419.1 Txe/YoeB family addiction module toxin Toxin
NYE86_RS03360 (NYE86_03360) 764453..765499 - 1047 WP_259437420.1 rod shape-determining protein -
NYE86_RS03365 (NYE86_03365) 765496..765963 - 468 WP_259437421.1 hypothetical protein -
NYE86_RS03370 (NYE86_03370) 766187..766402 - 216 WP_259437422.1 dodecin family protein -
NYE86_RS03375 (NYE86_03375) 766524..767609 + 1086 WP_259437423.1 PP2C family protein-serine/threonine phosphatase -
NYE86_RS03380 (NYE86_03380) 767631..768998 - 1368 WP_259437424.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10287.71 Da        Isoelectric Point: 9.4413

>T256873 WP_259437419.1 NZ_CP103871:764151-764411 [Actinacidiphila bryophytorum]
VKIVFASRAWEDYLWWQVQDRRVLKRINTLIADVARNGNEGIGKPEPLKHGFQGYWSRRINDEHRLIYKVVDDSVLIAQC
RYHYES

Download         Length: 261 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9443.47 Da        Isoelectric Point: 4.2712

>AT256873 WP_259442673.1 NZ_CP103871:763897-764154 [Actinacidiphila bryophytorum]
VKTMSYSESRAKYAEVLNSVTDDREEVVITRAGHDPVVIVSLEDYESLKETAYLLRSPANARRLLASIEELESGGGTVRE
LAEEE

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References