Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1271636..1272553 Replicon chromosome
Accession NZ_CP103856
Organism Bacillus velezensis strain SRCM116265

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag NX081_RS06665 Protein ID WP_032866111.1
Coordinates 1271807..1272553 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID -
Locus tag NX081_RS06660 Protein ID WP_060561801.1
Coordinates 1271636..1271806 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX081_RS06620 (1266861) 1266861..1268492 + 1632 WP_060561803.1 pyocin knob domain-containing protein -
NX081_RS06625 (1268505) 1268505..1268876 + 372 WP_060561802.1 XkdW family protein -
NX081_RS06630 (1268881) 1268881..1269078 + 198 WP_059367156.1 XkdX family protein -
NX081_RS06635 (1269135) 1269135..1269895 + 761 Protein_1246 phage portal protein -
NX081_RS06640 (1269947) 1269947..1270210 + 264 WP_003154815.1 hemolysin XhlA family protein -
NX081_RS06645 (1270224) 1270224..1270487 + 264 WP_003154813.1 phage holin -
NX081_RS06650 (1270501) 1270501..1271379 + 879 WP_043021264.1 N-acetylmuramoyl-L-alanine amidase -
NX081_RS06655 (1271414) 1271414..1271539 - 126 WP_023356844.1 hypothetical protein -
NX081_RS06660 (1271636) 1271636..1271806 - 171 WP_060561801.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
NX081_RS06665 (1271807) 1271807..1272553 - 747 WP_032866111.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
NX081_RS06670 (1272658) 1272658..1273656 - 999 WP_007407255.1 inorganic phosphate transporter -
NX081_RS06675 (1273669) 1273669..1274286 - 618 WP_003154804.1 DUF47 domain-containing protein -
NX081_RS06680 (1274572) 1274572..1275888 - 1317 WP_007610842.1 amino acid permease -
NX081_RS06685 (1276211) 1276211..1277161 + 951 WP_012117369.1 ring-cleaving dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1237844..1330083 92239


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29095.60 Da        Isoelectric Point: 4.7755

>T256807 WP_032866111.1 NZ_CP103856:c1272553-1271807 [Bacillus velezensis]
MLMFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6690.77 Da        Isoelectric Point: 10.9273

>AT256807 WP_060561801.1 NZ_CP103856:c1271806-1271636 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQLSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References