Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 1293025..1293686 Replicon chromosome
Accession NZ_CP103852
Organism Ralstonia pseudosolanacearum strain LMG 9673

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NY025_RS13890 Protein ID WP_193026209.1
Coordinates 1293025..1293438 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID D8N5P4
Locus tag NY025_RS13895 Protein ID WP_020749302.1
Coordinates 1293435..1293686 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NY025_RS13865 (NY025_13865) 1288431..1288721 - 291 WP_197366495.1 H-NS family nucleoid-associated regulatory protein -
NY025_RS13870 (NY025_13870) 1288903..1289898 - 996 WP_280926349.1 YopJ family acetyltransferase -
NY025_RS13875 (NY025_13875) 1290623..1290847 + 225 WP_230643474.1 DUF6441 family protein -
NY025_RS13880 (NY025_13880) 1290890..1291180 - 291 WP_193026211.1 H-NS family nucleoid-associated regulatory protein -
NY025_RS13885 (NY025_13885) 1291732..1292880 + 1149 WP_197366493.1 DNA cytosine methyltransferase -
NY025_RS13890 (NY025_13890) 1293025..1293438 - 414 WP_193026209.1 type II toxin-antitoxin system VapC family toxin Toxin
NY025_RS13895 (NY025_13895) 1293435..1293686 - 252 WP_020749302.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NY025_RS13900 (NY025_13900) 1293762..1297862 + 4101 WP_259423536.1 tape measure protein -
NY025_RS13905 (NY025_13905) 1297868..1298263 + 396 WP_197366423.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1267290..1307420 40130


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-63)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15742.09 Da        Isoelectric Point: 6.2337

>T256804 WP_193026209.1 NZ_CP103852:c1293438-1293025 [Ralstonia pseudosolanacearum]
MSYLIDTNVLSELRRKQPDARVLAWMQDRPRQSLYLSVLTLGEIRKGIERLDDAARRQHLIDWLETELPNYFLGRLLDVD
AHTADRWGRLMSSANRPLPAIDGLLAATALQHDLILVTRNTKDFVGLDVPLINPWET

Download         Length: 414 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9258.46 Da        Isoelectric Point: 5.0628

>AT256804 WP_020749302.1 NZ_CP103852:c1293686-1293435 [Ralstonia pseudosolanacearum]
MQSWQLQAAKARFSDVVKRAADDGPQEITVHGRPVAVVISRALFDRLSGSGESLVDFMRQSPLAGLDDVVFERERSLPRE
VDF

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A5B7U0Z6

References