Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1200682..1201226 Replicon chromosome
Accession NZ_CP103852
Organism Ralstonia pseudosolanacearum strain LMG 9673

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NY025_RS13440 Protein ID WP_193027890.1
Coordinates 1200682..1200957 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NY025_RS13445 Protein ID WP_193027891.1
Coordinates 1200957..1201226 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NY025_RS13410 (NY025_13410) 1196085..1196501 + 417 WP_193027885.1 hypothetical protein -
NY025_RS13415 (NY025_13415) 1196572..1197921 + 1350 WP_193027886.1 replication-associated recombination protein A -
NY025_RS13420 (NY025_13420) 1197988..1199304 + 1317 WP_193027887.1 serine--tRNA ligase -
NY025_RS13430 (NY025_13430) 1199528..1200091 + 564 WP_193027888.1 recombinase family protein -
NY025_RS13435 (NY025_13435) 1200069..1200629 - 561 WP_193027889.1 DUF2726 domain-containing protein -
NY025_RS13440 (NY025_13440) 1200682..1200957 - 276 WP_193027890.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NY025_RS13445 (NY025_13445) 1200957..1201226 - 270 WP_193027891.1 ribbon-helix-helix domain-containing protein Antitoxin
NY025_RS13450 (NY025_13450) 1201392..1201979 - 588 WP_230642671.1 NAD(P)H-dependent oxidoreductase -
NY025_RS13455 (NY025_13455) 1202170..1202580 - 411 WP_230642669.1 alpha/beta hydrolase -
NY025_RS13460 (NY025_13460) 1202633..1203649 + 1017 WP_193027114.1 IS21 family transposase -
NY025_RS13465 (NY025_13465) 1203646..1204434 + 789 WP_193027111.1 IS21-like element ISRso19 family helper ATPase IstB -
NY025_RS13470 (NY025_13470) 1204510..1204911 - 402 Protein_1116 alpha/beta hydrolase -
NY025_RS13475 (NY025_13475) 1205043..1205942 + 900 WP_193035960.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1196085..1205942 9857


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10630.33 Da        Isoelectric Point: 10.1779

>T256803 WP_193027890.1 NZ_CP103852:c1200957-1200682 [Ralstonia pseudosolanacearum]
MEVKWTGKAVSDITRLYEFLSQVNKPAAIRVVQSLTGAPKSLVVNPRIGEQLDEFEPREVRRIIVGQYEMRYAIRGSVIY
VLRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10056.37 Da        Isoelectric Point: 6.7268

>AT256803 WP_193027891.1 NZ_CP103852:c1201226-1200957 [Ralstonia pseudosolanacearum]
MAHLDTRVLTAHVPVQLAERVDQIAERLERSRGWIMKQALSAWIDQEEERSRLTREALADVDAGTVIDHQAVQAWADSLS
TSKPKKAPR

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References