Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 1049748..1050358 Replicon chromosome
Accession NZ_CP103851
Organism Ralstonia pseudosolanacearum strain LMG 9673

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NY025_RS04415 Protein ID WP_193029203.1
Coordinates 1050050..1050358 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NY025_RS04410 Protein ID WP_016722339.1
Coordinates 1049748..1050053 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NY025_RS04390 (NY025_04390) 1045084..1045281 + 198 Protein_871 IS5/IS1182 family transposase -
NY025_RS04395 (NY025_04395) 1045672..1047175 + 1504 Protein_872 group II intron reverse transcriptase/maturase -
NY025_RS04400 (NY025_04400) 1047238..1048026 + 789 Protein_873 IS5 family transposase -
NY025_RS04405 (NY025_04405) 1048222..1049535 - 1314 WP_193029205.1 MFS family transporter -
NY025_RS04410 (NY025_04410) 1049748..1050053 - 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
NY025_RS04415 (NY025_04415) 1050050..1050358 - 309 WP_193029203.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NY025_RS04420 (NY025_04420) 1050434..1051633 - 1200 WP_197366039.1 MFS transporter -
NY025_RS04425 (NY025_04425) 1051760..1052575 - 816 WP_197366040.1 GntR family transcriptional regulator -
NY025_RS04430 (NY025_04430) 1052753..1053304 - 552 WP_193029197.1 helix-turn-helix domain-containing protein -
NY025_RS04435 (NY025_04435) 1053437..1054030 + 594 WP_193029195.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1045672..1050367 4695
- flank IS/Tn - - 1047292..1048026 734


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11783.57 Da        Isoelectric Point: 7.1355

>T256799 WP_193029203.1 NZ_CP103851:c1050358-1050050 [Ralstonia pseudosolanacearum]
MLTIRTTEIFDDWFCSLRDKAAQRRIQVRIDRLQMGNPGDMKAVRDGIRELRIDHGPGYRLYVVQHGVVLIVLLCGGDKS
TQEADIRRAIDLSRRLDVDDME

Download         Length: 309 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT256799 WP_016722339.1 NZ_CP103851:c1050053-1049748 [Ralstonia pseudosolanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References