Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2050348..2050837 Replicon chromosome
Accession NZ_CP103834
Organism Actinobacillus genomosp.

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag NYR63_RS09590 Protein ID WP_279457315.1
Coordinates 2050348..2050608 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag NYR63_RS09595 Protein ID WP_279457316.1
Coordinates 2050595..2050837 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYR63_RS09555 (NYR63_09550) 2046326..2046601 + 276 WP_005599252.1 oxidative damage protection protein -
NYR63_RS09560 (NYR63_09555) 2046619..2047716 + 1098 WP_279457314.1 membrane-bound lytic murein transglycosylase MltC -
NYR63_RS09585 (NYR63_09580) 2048716..2050107 + 1392 WP_005609177.1 signal recognition particle protein -
NYR63_RS09590 (NYR63_09585) 2050348..2050608 + 261 WP_279457315.1 BrnT family toxin Toxin
NYR63_RS09595 (NYR63_09590) 2050595..2050837 + 243 WP_279457316.1 CopG family antitoxin Antitoxin
NYR63_RS09600 (NYR63_09595) 2050915..2052579 - 1665 WP_279457317.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -
NYR63_RS09605 (NYR63_09600) 2052772..2053938 - 1167 WP_279457318.1 FAD-dependent oxidoreductase -
NYR63_RS09610 (NYR63_09605) 2054144..2055670 + 1527 WP_279457319.1 YifB family Mg chelatase-like AAA ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2019303..2056883 37580


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(4-79)

Antitoxin

CopG antitoxin

(16-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10343.86 Da        Isoelectric Point: 10.1680

>T256786 WP_279457315.1 NZ_CP103834:2050348-2050608 [Actinobacillus genomosp. 1]
MFEYDPNKSRINKEKHGIDFEEAKQLWKDEQLLTFTVMNDPEHRLLAIGQINKKHWSAIFTVRGKNVRLISVRRSRKKEV
ELYENT

Download         Length: 261 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9385.73 Da        Isoelectric Point: 6.2244

>AT256786 WP_279457316.1 NZ_CP103834:2050595-2050837 [Actinobacillus genomosp. 1]
MKTHSLEFERKFDDNEEDIVEYLDLTSANRPNQKSKRVNVDFPIWMVESLDKEAQHLGVPRQALIKLWIAEKLPKPHIAS

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References