Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1954730..1955358 Replicon chromosome
Accession NZ_CP103809
Organism Actinobacillus genomosp.

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NYR62_RS08985 Protein ID WP_279475412.1
Coordinates 1954960..1955358 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NYR62_RS08980 Protein ID WP_279475411.1
Coordinates 1954730..1954960 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYR62_RS08975 (NYR62_08975) 1952576..1954207 + 1632 WP_279475410.1 hypothetical protein -
NYR62_RS08980 (NYR62_08980) 1954730..1954960 + 231 WP_279475411.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NYR62_RS08985 (NYR62_08985) 1954960..1955358 + 399 WP_279475412.1 tRNA(fMet)-specific endonuclease VapC Toxin
NYR62_RS08990 (NYR62_08990) 1955494..1955910 - 417 WP_005618204.1 DUF417 family protein -
NYR62_RS08995 (NYR62_08995) 1956156..1956806 + 651 WP_279475414.1 DUF2202 domain-containing protein -
NYR62_RS09000 (NYR62_09000) 1956880..1957539 - 660 WP_279475415.1 hypothetical protein -
NYR62_RS09005 (NYR62_09005) 1957853..1959175 - 1323 WP_279475416.1 HslU--HslV peptidase ATPase subunit -
NYR62_RS09010 (NYR62_09010) 1959230..1959751 - 522 WP_279475417.1 ATP-dependent protease subunit HslV -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1947247..1957539 10292


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(6-52)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15155.46 Da        Isoelectric Point: 8.1004

>T256699 WP_279475412.1 NZ_CP103809:1954960-1955358 [Actinobacillus genomosp. 1]
MLAYMLDTNIAIYVIKRRPIEVLDKFNLNSTRLCVSSITAAELYYGAEKSQFPERNMAVIEDFLSRLTILDYTHKAATHF
GNIKAHLSKHGKIIRENDIHVAAHARSEGLVLVTNNLREFERVEGLRLDNWV

Download         Length: 399 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8611.68 Da        Isoelectric Point: 4.5358

>AT256699 WP_279475411.1 NZ_CP103809:1954730-1954960 [Actinobacillus genomosp. 1]
MEASVFMTNRSQAVRLPAEVRFASDVKKLSVRVVGNERILAPINQSWDSFFLGSSTVSDDFMTEREISTQAEREEL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References