Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1443774..1444282 Replicon chromosome
Accession NZ_CP103809
Organism Actinobacillus genomosp.

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NYR62_RS06465 Protein ID WP_279474969.1
Coordinates 1444022..1444282 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NYR62_RS06460 Protein ID WP_279456843.1
Coordinates 1443774..1444025 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYR62_RS06420 (NYR62_06420) 1439144..1439692 - 549 WP_279474965.1 type IV pilus biogenesis/stability protein PilW -
NYR62_RS06425 (NYR62_06425) 1439746..1440927 - 1182 WP_279474968.1 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN -
NYR62_RS06450 (NYR62_06450) 1441834..1443273 + 1440 WP_279456842.1 glutamate--tRNA ligase -
NYR62_RS06460 (NYR62_06460) 1443774..1444025 + 252 WP_279456843.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
NYR62_RS06465 (NYR62_06465) 1444022..1444282 + 261 WP_279474969.1 Txe/YoeB family addiction module toxin Toxin
NYR62_RS06470 (NYR62_06470) 1444439..1444606 - 168 WP_279468242.1 Trm112 family protein -
NYR62_RS06475 (NYR62_06475) 1444608..1445588 - 981 WP_279474970.1 tetraacyldisaccharide 4'-kinase -
NYR62_RS06480 (NYR62_06480) 1445682..1446941 - 1260 WP_279456847.1 ATP-dependent protease ATP-binding subunit ClpX -
NYR62_RS06485 (NYR62_06485) 1446941..1447531 - 591 WP_005598326.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP -
NYR62_RS06490 (NYR62_06490) 1447653..1448033 + 381 WP_279474971.1 SufE family protein -
NYR62_RS06495 (NYR62_06495) 1448036..1448824 - 789 WP_279474972.1 glycosyltransferase family A protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10421.97 Da        Isoelectric Point: 8.0109

>T256696 WP_279474969.1 NZ_CP103809:1444022-1444282 [Actinobacillus genomosp. 1]
MKLTFSSNAWEDYLYWQKTDKIILKRINSLIKDIQRQPFEGIGKPEPLKFNLSGFWSRRINEEHRLIYTVEDEAILIVAC
RYHYDQ

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9348.64 Da        Isoelectric Point: 4.5509

>AT256696 WP_279456843.1 NZ_CP103809:1443774-1444025 [Actinobacillus genomosp. 1]
MQAITYTEARQNLAGTMSKVAEDFEPILITRSKGGNCVLMSYEQYCSLEETAYLMRSPTNAKRLLDSVAELRQGQGIERD
LIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References