Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2011032..2011660 Replicon chromosome
Accession NZ_CP103808
Organism Actinobacillus genomosp.

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NYR61_RS09385 Protein ID WP_279468585.1
Coordinates 2011262..2011660 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NYR61_RS09380 Protein ID WP_279468584.1
Coordinates 2011032..2011262 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYR61_RS09370 (NYR61_09370) 2008879..2010438 + 1560 WP_279468583.1 hypothetical protein -
NYR61_RS09375 (NYR61_09375) 2010784..2010957 - 174 Protein_1804 addiction module antidote protein, HigA family -
NYR61_RS09380 (NYR61_09380) 2011032..2011262 + 231 WP_279468584.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NYR61_RS09385 (NYR61_09385) 2011262..2011660 + 399 WP_279468585.1 tRNA(fMet)-specific endonuclease VapC Toxin
NYR61_RS09390 (NYR61_09390) 2011795..2012211 - 417 WP_005609158.1 DUF417 family protein -
NYR61_RS09395 (NYR61_09395) 2012458..2013090 + 633 WP_279468586.1 DUF2202 domain-containing protein -
NYR61_RS09400 (NYR61_09400) 2013290..2014069 - 780 WP_279468587.1 hypothetical protein -
NYR61_RS09405 (NYR61_09405) 2014142..2015464 - 1323 WP_005620148.1 HslU--HslV peptidase ATPase subunit -
NYR61_RS09410 (NYR61_09410) 2015519..2016040 - 522 WP_005618211.1 ATP-dependent protease subunit HslV -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1998661..2014069 15408


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(6-52)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15086.35 Da        Isoelectric Point: 7.0614

>T256694 WP_279468585.1 NZ_CP103808:2011262-2011660 [Actinobacillus genomosp. 1]
MLTYMLDTNIAIYVIKRRPLEVLDKFNLNSTRLCVSSITAAELYYGAEKSQFPEQNMAVIEDFLSRLTILDYTHKEATHF
GNIKAHLSKHGKIIGENDIHIAAHARSEGLVLVTNNLREFERVEGLRLANWV

Download         Length: 399 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8545.71 Da        Isoelectric Point: 4.7063

>AT256694 WP_279468584.1 NZ_CP103808:2011032-2011262 [Actinobacillus genomosp. 1]
MEASVFMTNRSQAVRLPAEVRFASDVKKLSVRVVGNERILAPINQSWDSFFLGAATVSDDFMTEREISIQPEREGL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References