Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1503788..1504296 Replicon chromosome
Accession NZ_CP103808
Organism Actinobacillus genomosp.

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NYR61_RS06880 Protein ID WP_237611416.1
Coordinates 1504036..1504296 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NYR61_RS06875 Protein ID WP_279456843.1
Coordinates 1503788..1504039 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYR61_RS06835 (NYR61_06835) 1499158..1499706 - 549 WP_279468241.1 type IV pilus biogenesis/stability protein PilW -
NYR61_RS06840 (NYR61_06840) 1499760..1500941 - 1182 WP_279456841.1 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN -
NYR61_RS06865 (NYR61_06865) 1501848..1503287 + 1440 WP_279456842.1 glutamate--tRNA ligase -
NYR61_RS06875 (NYR61_06875) 1503788..1504039 + 252 WP_279456843.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
NYR61_RS06880 (NYR61_06880) 1504036..1504296 + 261 WP_237611416.1 Txe/YoeB family addiction module toxin Toxin
NYR61_RS06885 (NYR61_06885) 1504454..1504621 - 168 WP_279468242.1 Trm112 family protein -
NYR61_RS06890 (NYR61_06890) 1504623..1505602 - 980 Protein_1343 tetraacyldisaccharide 4'-kinase -
NYR61_RS06895 (NYR61_06895) 1505697..1506956 - 1260 WP_279456847.1 ATP-dependent protease ATP-binding subunit ClpX -
NYR61_RS06900 (NYR61_06900) 1506956..1507546 - 591 WP_005598326.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP -
NYR61_RS06905 (NYR61_06905) 1507668..1508048 + 381 WP_279468243.1 SufE family protein -
NYR61_RS06910 (NYR61_06910) 1508051..1508839 - 789 WP_279453514.1 glycosyltransferase family A protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10407.94 Da        Isoelectric Point: 8.0109

>T256691 WP_237611416.1 NZ_CP103808:1504036-1504296 [Actinobacillus genomosp. 1]
MKLTFSSNAWEDYLYWQKTDKIILKRINSLIKDIQRQPFEGIGKPEPLKFNLSGFWSRRINEEHRLIYSVEDEAILIVAC
RYHYDQ

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9348.64 Da        Isoelectric Point: 4.5509

>AT256691 WP_279456843.1 NZ_CP103808:1503788-1504039 [Actinobacillus genomosp. 1]
MQAITYTEARQNLAGTMSKVAEDFEPILITRSKGGNCVLMSYEQYCSLEETAYLMRSPTNAKRLLDSVAELRQGQGIERD
LIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References