Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DinJ
Location 3965134..3965650 Replicon chromosome
Accession NZ_CP103791
Organism Salmonella enterica subsp. enterica serovar Infantis strain MRS17_00712

Toxin (Protein)


Gene name relE Uniprot ID A0A623NIH5
Locus tag NYQ90_RS19085 Protein ID WP_023993574.1
Coordinates 3965134..3965418 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A633LVJ8
Locus tag NYQ90_RS19090 Protein ID WP_023993575.1
Coordinates 3965408..3965650 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYQ90_RS19070 (3960250) 3960250..3961902 + 1653 WP_023993572.1 alpha,alpha-phosphotrehalase -
NYQ90_RS19075 (3962311) 3962311..3964449 + 2139 WP_000187818.1 anaerobic ribonucleoside-triphosphate reductase -
NYQ90_RS19080 (3964666) 3964666..3965130 + 465 WP_023993573.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NYQ90_RS19085 (3965134) 3965134..3965418 - 285 WP_023993574.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NYQ90_RS19090 (3965408) 3965408..3965650 - 243 WP_023993575.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NYQ90_RS19095 (3965728) 3965728..3967641 - 1914 WP_023993576.1 BglG family transcription antiterminator -
NYQ90_RS19100 (3967658) 3967658..3968398 - 741 WP_023993577.1 KDGP aldolase family protein -
NYQ90_RS19105 (3968395) 3968395..3969513 - 1119 WP_023993578.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
NYQ90_RS19110 (3969497) 3969497..3970630 - 1134 WP_023993579.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10925.70 Da        Isoelectric Point: 9.8739

>T256678 WP_023993574.1 NZ_CP103791:c3965418-3965134 [Salmonella enterica subsp. enterica serovar Infantis]
MNYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARLNDLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8989.40 Da        Isoelectric Point: 5.0807

>AT256678 WP_023993575.1 NZ_CP103791:c3965650-3965408 [Salmonella enterica subsp. enterica serovar Infantis]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTLTLSDSEDALIQTVRERLSSPQKGIKVSLDEL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A623NIH5

Antitoxin

Source ID Structure
AlphaFold DB A0A633LVJ8

References