Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 840501..841161 Replicon chromosome
Accession NZ_CP103791
Organism Salmonella enterica subsp. enterica serovar Infantis strain MRS17_00712

Toxin (Protein)


Gene name cptA Uniprot ID A0A5I5GR00
Locus tag NYQ90_RS04040 Protein ID WP_000244761.1
Coordinates 840748..841161 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag NYQ90_RS04035 Protein ID WP_000351186.1
Coordinates 840501..840767 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYQ90_RS04015 (836430) 836430..837863 - 1434 WP_001230139.1 6-phospho-beta-glucosidase BglA -
NYQ90_RS04020 (838021) 838021..838332 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
NYQ90_RS04025 (838496) 838496..839155 + 660 WP_000250289.1 hemolysin III family protein -
NYQ90_RS04030 (839271) 839271..840251 - 981 WP_023260866.1 tRNA-modifying protein YgfZ -
NYQ90_RS04035 (840501) 840501..840767 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
NYQ90_RS04040 (840748) 840748..841161 + 414 WP_000244761.1 protein YgfX Toxin
NYQ90_RS04045 (841214) 841214..841735 - 522 WP_001055885.1 flavodoxin FldB -
NYQ90_RS04050 (841848) 841848..842744 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
NYQ90_RS04055 (842768) 842768..843481 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NYQ90_RS04060 (843487) 843487..845220 + 1734 WP_000813387.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16199.15 Da        Isoelectric Point: 10.7537

>T256668 WP_000244761.1 NZ_CP103791:840748-841161 [Salmonella enterica subsp. enterica serovar Infantis]
VVLWQSDLRVSWRAQWISLLIHGLVSAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT256668 WP_000351186.1 NZ_CP103791:840501-840767 [Salmonella enterica subsp. enterica serovar Infantis]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5I5GR00

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References