256640

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2409524..2410502 Replicon chromosome
Accession NZ_CP103777
Organism Bacillus toyonensis strain DC11

Toxin (Protein)


Gene name spoIISA Uniprot ID K0FNW8
Locus tag NYR47_RS12330 Protein ID WP_000155917.1
Coordinates 2409524..2410264 (+) Length 247 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag NYR47_RS12335 Protein ID WP_142311449.1
Coordinates 2410377..2410502 (+) Length 42 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYR47_RS12310 2405186..2405968 + 783 WP_097954109.1 class I SAM-dependent methyltransferase -
NYR47_RS12315 2406147..2407823 - 1677 WP_259417551.1 alpha-keto acid decarboxylase family protein -
NYR47_RS12320 2407950..2408432 + 483 WP_000196695.1 MarR family winged helix-turn-helix transcriptional regulator -
NYR47_RS12325 2408600..2409337 + 738 WP_259417552.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
NYR47_RS12330 2409524..2410264 + 741 WP_000155917.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
NYR47_RS12335 2410377..2410502 + 126 WP_142311449.1 D-alanyl-D-alanine carboxypeptidase Antitoxin
NYR47_RS12340 2410578..2410754 + 177 WP_000808012.1 stage II sporulation protein SB -
NYR47_RS12345 2410803..2411192 - 390 Protein_2349 YxeA family protein -
NYR47_RS12350 2411436..2412905 + 1470 WP_000287513.1 beta-Ala-His dipeptidase -
NYR47_RS12355 2413218..2414027 + 810 WP_259417553.1 papain-like cysteine protease family protein -
NYR47_RS12360 2414055..2414657 + 603 WP_259417554.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(10-244)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 247 a.a.        Molecular weight: 28446.03 Da        Isoelectric Point: 7.3946

>T256640 WP_000155917.1 NZ_CP103777:2409524-2410264 [Bacillus toyonensis]
MTISNIRIGLFILAIVFVVLVFFYWRNEELYEEKKQRIRKTWYGLFITSVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIS
FILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTNIIQNINPAAFGTMEWHTEEEYTKSLNTFLDSYGEKIGAK
IVVFEAANELNTGFRGIRSQFSITIPIEHIEQLNEQKAVQVENVGIIPAKIMNDVFIVIDGKKNSLQDRDFENVYNLTIH
HSYFSK

Download         Length: 741 bp

Antitoxin


Download         Length: 42 a.a.        Molecular weight: 4937.36 Da        Isoelectric Point: 3.9798

>AT256640 WP_142311449.1 NZ_CP103777:2410377-2410502 [Bacillus toyonensis]
VINDYDNDFFKEENEDTTDFSLIKGDTLQQVEKLEEELKRK

Download         Length: 126 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB K0FNW8

Antitoxin

Source ID Structure

References